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妊娠剧吐水平预测(HELP评分)可识别患有严重疾病指标的患者:一项验证研究。

HyperEmesis Level Prediction (HELP Score) Identifies Patients with Indicators of Severe Disease: a Validation Study.

作者信息

MacGibbon Kimber W, Kim Sarah, Mullin Patrick M, Fejzo Marlena S

机构信息

HER Foundation, Damascus, OR, USA.

Brown University, Providence, RI, USA.

出版信息

Geburtshilfe Frauenheilkd. 2021 Jan;81(1):90-98. doi: 10.1055/a-1309-1997. Epub 2021 Jan 19.

DOI:10.1055/a-1309-1997
PMID:33487669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7815331/
Abstract

Hyperemesis gravidarum (HG) severity can be underestimated resulting in undertreatment and adverse outcomes. This study was conducted to validate a tool (HELP Score) designed to score HG severity. A survey link which included PUQE and HELP Score (HELP) tool questions was posted on websites related to HG. HELP scores were compared to PUQE scores for indicators of severe disease. HELP classified 92% of women reporting "nothing goes or stays down" as severe, compared to 58% using PUQE. Women self-categorizing symptoms as severe were more likely categorized as severe using HELP. Women hospitalized for HG were more likely classified as severe using HELP. HELP performs better than PUQE in identifying patients with severe symptoms requiring intervention. This study provides a novel tool that should be implemented to determine the need for intervention for NVP that may be overlooked using PUQE or empirical assessment.

摘要

妊娠剧吐(HG)的严重程度可能被低估,从而导致治疗不足和不良后果。本研究旨在验证一种用于评估HG严重程度的工具(HELP评分)。一个包含PUQE和HELP评分(HELP)工具问题的调查链接被发布在与HG相关的网站上。将HELP评分与PUQE评分进行比较,以作为严重疾病的指标。HELP将92%报告“吃什么吐什么”的女性归类为严重,而使用PUQE的这一比例为58%。自我将症状归类为严重的女性使用HELP更有可能被归类为严重。因HG住院的女性使用HELP更有可能被归类为严重。在识别需要干预的严重症状患者方面,HELP比PUQE表现更好。本研究提供了一种新工具,应采用该工具来确定对于可能被PUQE或经验性评估忽视的恶心和呕吐妊娠反应(NVP)进行干预的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c8/7815331/9fffbf0baf32/10-1055-a-1309-1997-igf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c8/7815331/9fffbf0baf32/10-1055-a-1309-1997-igf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c8/7815331/9fffbf0baf32/10-1055-a-1309-1997-igf01.jpg

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Am J Perinatol. 2021 Feb;38(3):265-272. doi: 10.1055/s-0039-1696670. Epub 2019 Oct 3.
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Nausea and vomiting of pregnancy and hyperemesis gravidarum.妊娠恶心和呕吐及妊娠剧吐。
Nat Rev Dis Primers. 2019 Sep 12;5(1):62. doi: 10.1038/s41572-019-0110-3.
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Maternal vomiting during early pregnancy and cardiovascular risk factors at school age: the Generation R Study.孕期早期的母体呕吐与学龄期心血管危险因素:Generation R研究
Validity and internal consistency of the HELP Scor einstrument for assessing the severity of hyperemesis gravidarum symptoms.
用于评估妊娠剧吐症状严重程度的HELP评分工具的效度和内部一致性。
Rev Colomb Obstet Ginecol. 2024 Nov 28;75(4):4237. doi: 10.18597/rcog.4237.
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Gastrointestinal symptoms and disorders of gut-brain interaction in pregnancy.孕期的胃肠道症状及肠-脑互动障碍
Indian J Gastroenterol. 2025 Jan 4. doi: 10.1007/s12664-024-01705-z.
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Risk Factors for Infusions, Emergency Room Visits and Hospitalizations for Hyperemesis Gravidarum: New Data and Literature Review.妊娠剧吐的输液、急诊就诊及住院的危险因素:新数据与文献综述
Int J Womens Health. 2024 Oct 30;16:1789-1802. doi: 10.2147/IJWH.S371458. eCollection 2024.
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Assessment of management approaches for hyperemesis gravidarum and nausea and vomiting of pregnancy: a retrospective questionnaire analysis.妊娠剧吐和妊娠恶心呕吐管理方法评估:回顾性问卷调查分析。
BMC Pregnancy Childbirth. 2022 Aug 1;22(1):609. doi: 10.1186/s12884-022-04922-6.
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Usability of Pregnancy-Unique Quantification of Emesis questionnaire in women hospitalised for hyperemesis gravidarum: a prospective cohort study.用于妊娠剧吐住院妇女的呕吐定量问卷的可用性:一项前瞻性队列研究。
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