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食管切除术中环扎式食管胃吻合术:25mm 和 28mm 圆形吻合器吻合口不足和狭窄率无差异。

The Circular Stapled Esophagogastric Anastomosis in Esophagectomy: No Differences in Anastomotic Insufficiency and Stricture Rates Between the 25 mm and 28 mm Circular Stapler.

机构信息

Department of General, Visceral and Transplant Surgery, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of Leipzig, Leipzig, Germany.

出版信息

J Gastrointest Surg. 2021 Sep;25(9):2242-2249. doi: 10.1007/s11605-020-04895-x. Epub 2021 Jan 27.

Abstract

BACKGROUND

For patients undergoing an Ivor Lewis esophagectomy with a circular stapled anastomosis, the optimal diameter of the used circular stapler to restore continuity is unknown. The aim of this study was to compare the 25 mm stapled versus the 28 mm stapled esophagogastric anastomosis after Ivor Lewis esophagectomy, focusing on anastomotic insufficiency and postoperative anastomotic strictures.

METHODS

Between February 2008 and June 2019, 349 consecutive patients underwent Ivor Lewis esophagectomy with gastric conduit reconstruction and circular stapled anastomosis. Patient characteristics and postoperative results, such as anastomotic insufficiency rates, postoperative anastomotic stricture rates, time to anastomotic stricture rate, and the number of dilatations, were recorded in a prospective database and analyzed.

RESULTS

In 222 patients (64%), the 25 mm circular stapler was used and in 127 patients (36%) the 28 mm circular stapler was used. There were no differences in baseline characteristics. Anastomotic insufficiency rates were comparable between the 25 mm (12%) and the 28 mm groups (11%) (p = 0.751). There were no differences between postoperative anastomotic strictures in the 25 mm (14%) and the 28 mm groups (14%) (p = 0.863). Within patients with postoperative anastomotic strictures, a median number of 2 dilatations were observed in each group (p = 0.573) without differences in the time to first diagnosis (p = 0.412).

CONCLUSION

There were no differences in anastomotic insufficiency and postoperative anastomotic stricture rates between the 25 mm and the 28 mm circular stapled esophagogastric anastomosis after Ivor Lewis esophagectomy. Both the 25 mm and 28 mm stapler can be safely used to create a circular stapled esophagogastric anastomosis to restore continuity after esophagectomy.

摘要

背景

对于接受 Ivor Lewis 食管切除术并使用圆形吻合器吻合的患者,用于重建连续性的吻合器的最佳直径尚不清楚。本研究的目的是比较 Ivor Lewis 食管切除术后使用 25mm 和 28mm 吻合器吻合的食管胃吻合口,重点关注吻合口不足和术后吻合口狭窄。

方法

2008 年 2 月至 2019 年 6 月,连续 349 例患者接受 Ivor Lewis 食管切除术和胃管重建及圆形吻合术。患者特征和术后结果(如吻合口不足发生率、术后吻合口狭窄发生率、吻合口狭窄发生率时间和扩张次数)记录在一个前瞻性数据库中,并进行了分析。

结果

在 222 例患者(64%)中使用了 25mm 圆形吻合器,在 127 例患者(36%)中使用了 28mm 圆形吻合器。两组患者的基线特征无差异。25mm 组(12%)和 28mm 组(11%)的吻合口不足发生率无差异(p=0.751)。25mm 组(14%)和 28mm 组(14%)术后吻合口狭窄无差异(p=0.863)。在术后吻合口狭窄的患者中,两组患者均接受了中位数为 2 次扩张治疗(p=0.573),且首次诊断时间无差异(p=0.412)。

结论

Ivor Lewis 食管切除术后,使用 25mm 和 28mm 圆形吻合器吻合的食管胃吻合口在吻合口不足和术后吻合口狭窄发生率方面无差异。25mm 和 28mm 吻合器均可安全地用于食管切除术后重建连续性的圆形吻合器吻合。

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