Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, 665 Elm Street, Buffalo, NY, 14203, USA.
Department of Surgery, Mount Sinai Medical Center, Miami Beach, FL, USA.
J Gastrointest Surg. 2020 Aug;24(8):1729-1735. doi: 10.1007/s11605-019-04320-y. Epub 2019 Jul 16.
Minimally invasive foregut surgery is increasingly performed for both benign and malignant diseases. We present a retrospective series of patients who underwent minimally invasive Ivor Lewis esophagectomy (MIE) with linear stapled anastomosis performed at two centers in the USA, with a focus on evaluating leak and stricture rates.
Patients treated from 2007 to 2018 were included, and data on demographics, oncologic treatment, pathology, and outcomes were analyzed. The surgical technique utilized laparoscopic and thoracoscopic access, with an intrathoracic esophagogastric anastomosis using a 6-cm linear stapled side-to-side technique.
A total of 124 patients were included and 114 resections (91.9%) were completed in a minimally invasive fashion with a 6-cm linear stapled side-to-side anastomosis. Patients were predominantly male (90.7%) with a median age of 66.0 years and body mass index of 28.8 kg/m. Of 121 patients with malignancy, negative margins were obtained in 94.3% and median lymph node yield was 15 (IQR 12-22). In the intention to treat analysis, median operative time was 463 min (IQR 403-515), blood loss was 150 mL (IQR 100-200), and length of stay was 8 days (IQR 7-11). Postoperative complications were experienced by 64 patients (51.6%) including respiratory failure in 14 (11.3%) and pneumonia in 12 (9.7%). In patients who successfully underwent a 6-cm stapled side-to-side anastomosis, anastomotic leaks occurred in 6 patients (5.1%) without need for operative intervention, and anastomotic strictures occurred in 6 patients (5.1%) requiring endoscopic management.
Ivor Lewis MIE with a 6-cm linear stapled anastomosis can be completed with a high technical success rate, and low rates of anastomotic leak and stricture.
微创上消化道手术越来越多地用于治疗良性和恶性疾病。我们报告了在美国两个中心进行的微创 Ivor Lewis 食管切除术(MIE)的回顾性系列病例,重点评估吻合口漏和狭窄的发生率。
纳入了 2007 年至 2018 年期间接受治疗的患者,分析了人口统计学、肿瘤治疗、病理学和结局数据。手术技术采用腹腔镜和胸腔镜入路,在胸腔内使用 6cm 线性吻合器进行食管胃侧侧吻合。
共纳入 124 例患者,其中 114 例(91.9%)采用微创方式完成 6cm 线性吻合器侧侧吻合术。患者主要为男性(90.7%),中位年龄为 66.0 岁,体重指数为 28.8kg/m。121 例恶性肿瘤患者中,94.3%获得阴性切缘,中位淋巴结检出数为 15(IQR 12-22)。在意向治疗分析中,中位手术时间为 463 分钟(IQR 403-515),术中出血量为 150ml(IQR 100-200),住院时间为 8 天(IQR 7-11)。64 例(51.6%)患者发生术后并发症,包括呼吸衰竭 14 例(11.3%)和肺炎 12 例(9.7%)。在成功完成 6cm 吻合器侧侧吻合的患者中,吻合口漏发生在 6 例(5.1%)患者中,无需手术干预,吻合口狭窄发生在 6 例(5.1%)患者中,需要内镜治疗。
Ivor Lewis MIE 采用 6cm 线性吻合器吻合,技术成功率高,吻合口漏和狭窄发生率低。