Horsburgh C R, Holmberg S D
AIDS Program, Centers for Disease Control, Atlanta, Georgia.
Transfusion. 1988 Mar-Apr;28(2):192-5. doi: 10.1046/j.1537-2995.1988.28288179031.x.
We reviewed published reports of infection with human immunodeficiency virus type 2 (HIV-2) to provide a picture of its geographic distribution, pathogenicity, modes of transmission, and risk to the blood supply. Since the first reports in 1986, 627 HIV-2-seropositive persons have been reported; 604 of these were in natives of West Africa. Acquired immunodeficiency syndrome (AIDS) had developed in 42 patients, while 8 patients had AIDS-related complex. Transmission by sexual intercourse was the usual reported mode of spread. The modes of transmission of HIV-2 are thought to be the same as those for HIV-1, but perinatal transmission and transmission by sharing of needles among intravenous drug abusers have not yet been reported. The virus has not been identified in blood donors in the United States or West Germany, but two HIV-2-infected blood donors were reported in France. Further epidemiologic studies are needed to define the spectrum of disease, modes of transmission, and risk of HIV-2 to the blood supply.
我们查阅了已发表的关于2型人类免疫缺陷病毒（HIV-2）感染的报告，以了解其地理分布、致病性、传播方式以及对血液供应的风险。自1986年首次报告以来，已报告627例HIV-2血清反应阳性者；其中604例是西非本地人。42例患者已发展为获得性免疫缺陷综合征（AIDS），8例患者患有艾滋病相关综合征。性交传播是通常报告的传播方式。HIV-2的传播方式被认为与HIV-1相同，但围产期传播以及静脉吸毒者共用针头传播尚未见报告。在美国或西德的献血者中尚未发现该病毒，但法国报告了两名感染HIV-2的献血者。需要进一步的流行病学研究来确定疾病谱、传播方式以及HIV-2对血液供应的风险。
