Yadav Dharmveer, Birdi Amandeep, Tomo Sojit, Charan Jaykaran, Bhardwaj Pankaj, Sharma Praveen
Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, Rajasthan India.
Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan India.
Indian J Clin Biochem. 2021 Oct;36(4):492-497. doi: 10.1007/s12291-020-00950-1. Epub 2021 Feb 3.
COVID-19 has been declared a global pandemic by WHO on 11 March 2020. Still, very little is known about the potential protective dietary factors for the prevention of infection and mortality due to COVID-19. Keeping in view the scarcity of literature/studies available, in this regards present study was undertaken to assess if there is any correlation between mean levels of Vitamin D in various Asia Pacific countries with the infection and mortality caused by COVID-19. We collected data for mean levels of Vitamin D for 37 Asia Pacific countries for which we have also got the data regarding the morbidity and mortality of COVID-19. The mean levels of Vitamin D were found to have a significant association with the number of cases/million(r = - 0.394, value = 0.016) and a weak association with the number of deaths/ million (r = - 0.280, value = 0.093) due to COVID-19. In conclusion, we found a significant relationship between Vitamin D levels with the number of COVID-19 cases. So further clinical trial/study with a large sample size is needed to elucidate the protective role of Vitamin D in COVID-19.
2020年3月11日，世界卫生组织宣布新型冠状病毒肺炎（COVID-19）为全球大流行病。然而，对于预防COVID-19感染和死亡的潜在保护性饮食因素，我们仍知之甚少。鉴于现有文献/研究稀缺，本研究旨在评估亚太地区各国维生素D平均水平与COVID-19所致感染和死亡之间是否存在关联。我们收集了37个亚太国家的维生素D平均水平数据，同时也获取了这些国家COVID-19的发病率和死亡率数据。结果发现，维生素D平均水平与每百万病例数存在显著关联（r = -0.394，p值 = 0.016），与每百万死亡数存在弱关联（r = -0.280，p值 = 0.093）。总之，我们发现维生素D水平与COVID-19病例数之间存在显著关系。因此，需要进一步开展大样本量的临床试验/研究，以阐明维生素D在COVID-19中的保护作用。
