Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, United Kingdom; Potsdam Institute for Climate Impact Research, Telegrafenberg A 31, 14473 Potsdam, Germany.
Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, United Kingdom.
Sci Total Environ. 2021 May 1;767:145413. doi: 10.1016/j.scitotenv.2021.145413. Epub 2021 Jan 26.
Bats are the likely zoonotic origin of several coronaviruses (CoVs) that infect humans, including SARS-CoV-1 and SARS-CoV-2, both of which have caused large-scale epidemics. The number of CoVs present in an area is strongly correlated with local bat species richness, which in turn is affected by climatic conditions that drive the geographical distributions of species. Here we show that the southern Chinese Yunnan province and neighbouring regions in Myanmar and Laos form a global hotspot of climate change-driven increase in bat richness. This region coincides with the likely spatial origin of bat-borne ancestors of SARS-CoV-1 and SARS-CoV-2. Accounting for an estimated increase in the order of 100 bat-borne CoVs across the region, climate change may have played a key role in the evolution or transmission of the two SARS CoVs.
蝙蝠可能是几种感染人类的冠状病毒（CoV）的动物宿主，包括导致大规模疫情的 SARS-CoV-1 和 SARS-CoV-2。一个地区存在的 CoV 数量与当地蝙蝠物种丰富度密切相关，而蝙蝠物种丰富度又受到驱动物种地理分布的气候条件的影响。本研究表明，中国南部云南省以及缅甸和老挝的邻近地区形成了一个气候变化驱动下蝙蝠丰富度增加的全球热点地区。这一地区与 SARS-CoV-1 和 SARS-CoV-2 的蝙蝠源性祖先的可能空间起源相吻合。考虑到该地区预计会增加约 100 种蝙蝠源性 CoV，气候变化可能在两种 SARS CoV 的进化或传播中发挥了关键作用。
Zotero 插件
