9098Royal Trinity Hospice, London, UK.
Marie Curie Palliative Care Research Department, 4919UCL, London, UK.
Am J Hosp Palliat Care. 2021 Dec;38(12):1488-1494. doi: 10.1177/1049909121994299. Epub 2021 Feb 15.
Virtual Reality can help alleviate symptoms in a non-palliative care population. Personalized therapy can further alleviate these symptoms. There is little evidence in a palliative care population.
To understand the feasibility of repeated personalized virtual reality sessions in a palliative care population.
A feasibility randomized control trial. Intervention: personalized virtual reality, Control: non-personalized virtual reality. All participants completed a 4-minute virtual reality session for 4 weeks. At each point, the Edmonton Symptom Assessment System-Revised (scored 0 = none up to 100 = worst) was completed pre- and post- each session. A time-series regression analysis was completed for the overall effect.
SETTING/PARTICIPANTS: The research took place in one hospice. The main inclusion criteria was: (1) under the care of the hospice (2) advanced disease (3) over 18 years (4) physically able to use virtual reality set (5) capacity (6) proficient English.
Twenty-six participants enrolled, of which 20 (77%) completed all sessions. At baseline, the intervention group had a mean pre- score of 26.3 (SD 15.1) which reduced to 11.5 (SD 12.6) after the first session. At the same time point, the control group had a mean pre- score of 37.9 (SD 21.6) which reduced to 25.5 (SD 17.4) post-session. The mean scores dropped following each session, however this was not significant (mean difference = -1.3, 95% CI: -6.4 to 3.7, p = 0.601).
It is feasible to complete repeated virtual reality sessions within a palliative care population. Future research should explore the structure and effectiveness of virtual reality in a fully powered trial.
虚拟现实可以帮助缓解非姑息治疗人群的症状。个性化治疗可以进一步缓解这些症状。姑息治疗人群中几乎没有证据。
了解在姑息治疗人群中重复进行个性化虚拟现实治疗的可行性。
一项可行性随机对照试验。干预措施：个性化虚拟现实，对照组：非个性化虚拟现实。所有参与者在 4 周内完成了 4 分钟的虚拟现实治疗。在每个时间点，均在每次治疗前后使用修订后的埃德蒙顿症状评估系统（评分 0 表示无，100 表示最严重）进行评估。采用时间序列回归分析评估整体效果。
地点/参与者：研究在一家临终关怀医院进行。主要纳入标准为：（1）在临终关怀机构的照护下；（2）患有晚期疾病；（3）年龄超过 18 岁；（4）身体能够使用虚拟现实设备；（5）有能力；（6）精通英语。
共有 26 名参与者入组，其中 20 名（77%）完成了所有治疗。在基线时，干预组的平均治疗前评分为 26.3（SD 15.1），第一次治疗后降至 11.5（SD 12.6）。在同一时间点，对照组的平均治疗前评分为 37.9（SD 21.6），治疗后降至 25.5（SD 17.4）。每次治疗后，平均评分均有所下降，但无统计学意义（平均差值=-1.3，95%CI：-6.4 至 3.7，p=0.601）。
在姑息治疗人群中完成重复虚拟现实治疗是可行的。未来的研究应在充分验证的试验中探索虚拟现实的结构和有效性。
