Department of Food Science and Technology, University of Kashmir, Srinagar, 190006, India.
Department of Food Science and Technology, University of Kashmir, Srinagar, 190006, India.
Carbohydr Polym. 2021 Apr 15;258:117664. doi: 10.1016/j.carbpol.2021.117664. Epub 2021 Jan 21.
β-Glucan nanoparticles were produced from cereal and fungal sources viz: oats, barley, and yeast using ball milling which is considered as a green technology. The β-glucan nanoparticles were evaluated using dynamic light scattering (DLS) and Fourier transform infra-spectroscopy (ATR-FTIR). The particle size, zeta potential, polydispersity index, antioxidant, anticancerous, antimicrobial and antihypertensive potential of β-glucan nanoparticles from different sources were also studied. The experimental results revealed that the average particle size for BN (Barley β-glucan nanoparticle), ON (Oats β-glucan nanoparticle), and YN (Yeast β-glucan nanoparticle) were 90.35, 83.55 and 77.44 nm and zeta potential were in the range of -27 to -6.3 mV. . There was an increase in antioxidant, antihyperglycemic and antihypertensive activity of BN, YN, and ON in comparison to native. Study reported increase in anticancerous activity upon size reduction. Also, antibacterial activity of BNT, ONT, YNT, BN, ON and YN against Gram-negative and Gram-positive (E.coli & Bacillus Subtilis) were studied. It was concluded that the β-glucan nanoparticles showed enhanced nutraceutical properties that might be due to the nanoreduction using green technology.
β-葡聚糖纳米颗粒由谷物和真菌来源（燕麦、大麦和酵母）通过球磨制成，球磨被认为是一种绿色技术。使用动态光散射（DLS）和傅里叶变换红外光谱（ATR-FTIR）对 β-葡聚糖纳米颗粒进行了评估。还研究了来自不同来源的 β-葡聚糖纳米颗粒的粒径、Zeta 电位、多分散指数、抗氧化、抗癌、抗菌和抗高血压潜力。实验结果表明，BN（大麦 β-葡聚糖纳米颗粒）、ON（燕麦 β-葡聚糖纳米颗粒）和 YN（酵母 β-葡聚糖纳米颗粒）的平均粒径分别为 90.35、83.55 和 77.44nm，Zeta 电位范围为-27 至-6.3mV。与天然产物相比，BN、YN 和 ON 的抗氧化、降血糖和降血压活性均有所提高。研究报道，粒径减小会提高抗癌活性。此外，还研究了 BNT、ONT、YNT、BN、ON 和 YN 对革兰氏阴性菌和革兰氏阳性菌（大肠杆菌和枯草芽孢杆菌）的抗菌活性。结论是，β-葡聚糖纳米颗粒显示出增强的营养特性，这可能是由于使用绿色技术进行纳米还原。
