Bolookat Eftekhar Rajab, Rich Laurie J, Paragh Gyorgy, Colegio Oscar R, Singh Anurag K, Seshadri Mukund
Laboratory for Translational Imaging, Center for Oral Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14263.
Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York 14263.
Appl Sci (Basel). 2020 Feb;10(3). doi: 10.3390/app10031024. Epub 2020 Feb 4.
Photoacoustic imaging (PAI) is a novel hybrid imaging modality that provides excellent optical contrast with the spatial resolution of ultrasound in vivo. The method is widely being investigated in the clinical setting for diagnostic applications in dermatology. In this report, we illustrate the utility of PAI as a non-invasive tool for imaging tattoos. Ten different samples of commercially available tattoo inks were examined for their optoacoustic properties in vitro. In vivo PAI of an intradermal tattoo on the wrist was performed in a healthy human volunteer. Black/gray, green, violet and blue colored pigments provided higher levels of PA signal compared to white, orange, red and yellow pigments in vitro. PAI provided excellent contrast and enabled accurate delineation of the extent of the tattoo in the dermis. Our results reveal the photoacoustic properties of tattoo inks and demonstrate the potential clinical utility of PAI for intradermal imaging of tattoos. PAI may be useful as a clinical adjunct for objective preoperative evaluation of tattoos and potentially to guide/monitor laser-based tattoo removal procedures.
光声成像（PAI）是一种新型的混合成像模式，在体内能提供与超声空间分辨率相当的出色光学对比度。该方法正在临床环境中广泛研究，用于皮肤科的诊断应用。在本报告中，我们阐述了PAI作为一种用于纹身成像的非侵入性工具的效用。对十种市售纹身墨水的不同样本进行了体外光声特性检测。在一名健康人类志愿者身上对腕部皮内纹身进行了体内PAI检测。与白色、橙色、红色和黄色颜料相比，黑色/灰色、绿色、紫色和蓝色颜料在体外提供了更高水平的PA信号。PAI提供了出色的对比度，并能够准确描绘真皮内纹身的范围。我们的结果揭示了纹身墨水的光声特性，并证明了PAI在纹身皮内成像方面的潜在临床效用。PAI作为纹身术前客观评估的临床辅助手段可能有用，并且有可能指导/监测基于激光的纹身去除程序。
