Department of Urology, University of Kansas Medical Center, Kansas City, USA.
Department of Urologic Sciences, Vancouver General Hospital, University of British Columbia, Vancouver, Canada.
World J Urol. 2021 Oct;39(10):3951-3956. doi: 10.1007/s00345-021-03619-3. Epub 2021 Feb 19.
The holmium-YAG (Ho:YAG) Laser system is the current gold standard for laser lithotripsy (LL). Super Pulse Thulium Fiber Laser (SPTF) has emerged as an effective alternative. We compared the temperature profile of both the 120 W Ho:YAG and the 60 W SPTF systems during ureteral lithotripsy.
Antegrade ureteroscopy with LL was performed in ex-vivo porcine kidneys with 3 mm Begostones. Intra-ureteral temperature was measured using one probe proximal and one distal to the site of lithotripsy. LL was performed using a 200 μm core fiber at dusting (SPTF-0.1 J, 200 Hz, SP; Ho:YAG-0.3 J, 70 Hz, LP) and fragmenting (0.8 J, 8 Hz, SP for both) settings for 5 s. Fifteen repetitions were recorded for each laser at each setting. Tissue samples of the ureter were collected for histological analysis.
There was a rise in temperature at the site of lithotripsy using both systems at every setting evaluated. The median temperatures were greater for the SPTF on the fragmenting setting (33.3 °C vs 30.0 °C, p = 0.004). On the dusting setting, the median temperature was not statistically greater for Ho:YAG (40.6 °C vs 35.8 °C, p = 0.064), (Graphic 1). Histological analysis did not show any signs of injury or necrosis in any of the tested settings.
Higher power settings used for dusting have a higher temperature rise in the ureter during lasering. Median ureteral intra-luminal temperature rise during LL was equivalent during dusting and higher in the SPTF during fragmentation, but neither reached the threshold for thermal injury based on the duration of exposure.
钬-YAG(Ho:YAG)激光系统是目前激光碎石术(LL)的金标准。超脉冲掺铥光纤激光(SPTF)已成为一种有效的替代方法。我们比较了 120W Ho:YAG 和 60W SPTF 系统在输尿管碎石术中的温度分布。
使用 3mm Begostones 在离体猪肾中进行经尿道逆行输尿管镜检查和激光碎石术。使用一个位于碎石部位近端和一个位于碎石部位远端的探头测量输尿管内温度。使用 200μm 芯光纤进行 LL,以撒粉(SPTF-0.1J,200Hz,SP;Ho:YAG-0.3J,70Hz,LP)和粉碎(0.8J,8Hz,SP 用于两种情况)设置进行 5 秒。每种激光在每种设置下记录 15 次重复。收集输尿管组织样本进行组织学分析。
在每种评估的设置下,两种系统在碎石部位都出现了温度升高。在粉碎设置下,SPTF 的中位温度更高(33.3°C 比 30.0°C,p=0.004)。在撒粉设置下,Ho:YAG 的中位温度升高没有统计学意义(40.6°C 比 35.8°C,p=0.064)(图 1)。在任何测试设置下,组织学分析均未显示任何损伤或坏死迹象。
在激光碎石术中,用于撒粉的更高功率设置会导致输尿管内温度升高。在撒粉期间,LL 期间输尿管腔内中位温度升高相等,在粉碎期间 SPTF 更高,但两者均未达到基于暴露时间的热损伤阈值。