Cairo University, Giza, Egypt.
J Prim Care Community Health. 2021 Jan-Dec;12:2150132720980952. doi: 10.1177/2150132720980952.
Cardiovascular disease (CVD) is the most leading cause of mortality worldwide. Changes in diet can reduce subclinical cardiac injury and inflammation in parallel with reductions of other CVD risk factors.
The study aimed to evaluate the beneficial effect of the DASH diet versus usual healthy dietary advice (HDA) on the estimated risk of atherosclerotic cardiovascular disease (ASCVD).
It was a prospective interventional nonrandomized controlled study, conducted on 92 participants attending Family Medicine Outpatient Clinics, Cairo University. The participants were assigned to 2 dietary groups, the DASH and HDA groups, for 12 weeks. All subjects were subjected to anthropometric measurement, assessment of lipid profile, and the estimated cardiovascular risk pre-and post-intervention.
The estimated cardiovascular risk was reduced significantly in both the DASH and HDA groups, with no statistically significant difference between the 2 groups regarding the risk reduction. By comparing the percent change between pre and post-intervention in both DASH and HDA groups, the following are the results: BMI dropped by 6.5% versus 2.5%, systolic blood pressure decreased by 6.9% and 4.1%, fasting blood sugar dropped by 5.5% and 3.1%, total cholesterol dropped by 5.2% and 3.1%, LDL dropped by 8.2%, and 3.1%, and HDL increased by 8.2% and 2.4%, in DASH and HDA groups, respectively.
Both the DASH diet and HDA are associated with improvement in CVD risk factors. Although better risk factors decline with the DASH diet, there was no statistically significant difference between the 2 groups.
心血管疾病(CVD)是全球范围内导致死亡的最主要原因。饮食的改变可以减少亚临床心脏损伤和炎症,同时降低其他 CVD 风险因素。
本研究旨在评估 DASH 饮食与常规健康饮食建议(HDA)对动脉粥样硬化性心血管疾病(ASCVD)风险的有益影响。
这是一项前瞻性的干预性非随机对照研究,在开罗大学家庭医学门诊诊所进行,共纳入 92 名参与者。参与者被分为 2 个饮食组,即 DASH 组和 HDA 组,进行 12 周的饮食干预。所有受试者均接受了人体测量、血脂谱评估和干预前后的心血管风险评估。
DASH 组和 HDA 组的心血管风险均显著降低,但两组间风险降低无统计学差异。通过比较 DASH 组和 HDA 组干预前后的百分比变化,结果如下:BMI 分别下降了 6.5%和 2.5%,收缩压分别下降了 6.9%和 4.1%,空腹血糖分别下降了 5.5%和 3.1%,总胆固醇分别下降了 5.2%和 3.1%,LDL 分别下降了 8.2%和 3.1%,HDL 分别上升了 8.2%和 2.4%。
DASH 饮食和 HDA 都与 CVD 风险因素的改善相关。尽管 DASH 饮食可使更多的风险因素下降,但两组间无统计学差异。