New York State Veterinary Diagnostic Laboratory, Cornell University, 240 Farrier Road, Ithaca, New York 14850, USA.
Nassau County Department of Health, 200 County Seat Drive, Mineola, New York 11501, USA.
J Wildl Dis. 2021 Jan 6;57(1):145-156. doi: 10.7589/2018-02-035.
Vaccine-laden baits were distributed to interrupt and halt raccoon (Procyon lotor) rabies transmission in suburban Nassau and Suffolk counties on Long Island, New York, US. Fishmeal polymer baits containing the RABORAL V-RG® vaccine were deployed with helicopters, bait stations, and vehicles at a target density of 250 baits/km2 during annual September campaigns (2006-10). Semiannual campaigns (500 baits/km2) were also initiated in a portion of the treatment zone (2007-09) in response to a persistent focus of rabid raccoons. The last enzootic case was reported in January 2009. The final vaccination campaign was completed in 2010. The raccoon variant of rabies virus is no longer circulating in Nassau or Suffolk counties. Significantly greater probabilities of raccoon seroconversion were observed in helicopter-deployed bait zones. The lowest probabilities of seroconversion were identified in vehicle and bait station-deployment bait zones, with a marginal advantage associated with bait-station deployment. Seroconversion was negatively associated with developed, medium-intensity areas and increasing human population density. Significantly higher rabies virus neutralizing antibody endpoint titrations were detected in helicopter and bait station-deployment zones.
在美国纽约长岛的拿骚和萨福克县，为了阻断和阻止浣熊（Procyon lotor）狂犬病的传播，向浣熊投放了含有 RABORAL V-RG®疫苗的诱饵。2006 年至 2010 年期间，每年 9 月，使用直升机、诱饵站和车辆以 250 个诱饵/平方公里的目标密度部署含有鱼粉的聚合物诱饵。作为对持续存在的狂犬病浣熊集中区的回应，还在治疗区的一部分启动了半年度活动（500 个诱饵/平方公里）（2007-09 年）。2009 年 1 月报告了最后一个地方性病例。最后一次疫苗接种活动于 2010 年完成。狂犬病浣熊变异株不再在拿骚或萨福克县传播。在直升机投放诱饵区观察到浣熊血清转化率的概率显著增加。在车辆和诱饵站投放诱饵区，血清转化率最低，诱饵站投放具有边际优势。血清转化率与发达的中强度区域和人口密度的增加呈负相关。在直升机和诱饵站投放区检测到的狂犬病病毒中和抗体终点滴度显著升高。
