Department of "Organi di Senso", Sapienza University of Rome, Viale del Policlinico, 151-00161 Rome, Italy.
Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Via Carlo Forlanini, 34-47121 Forlì, Italy.
Am J Otolaryngol. 2021 Jul-Aug;42(4):102994. doi: 10.1016/j.amjoto.2021.102994. Epub 2021 Feb 20.
Analyze Extrusion&Exposion (E&E), its implications in the functional, anatomical results and subjective discomfort in OSA patients treated with Barbed Reposition Pharyngoplasty (BRP).
488 patients treated with BRP or multilevel TORS. Stratafix wire was used in 230 patients, V-Loc in 258. E&E, timing and localization evaluated at follow-up. Polygraphy used to assess the impact of E&E on functional results, PPOPS questionnaire used for subjective discomfort.
E&E in the entire group was 18,4%, with significant difference between Stratafix and V-Loc wire (p = 0,002), but not between BRP alone and multilevel surgery (p = 0,68). 28,9% of extrusion happened within the first seven days, 76,7% between seven days and two months, 5,5% after two months. Symptomatic clinical profile has been seen in 62,2%, asymptomatic one in 37,8% of patients. 35,5% of E&E were localized in tonsillar bed, 46,7% in soft palate and 20% in other sites. Mean delta-AHI of E&E patients was -15,87 ± 16.82 compared with one of those who did not have E&E was -16.34 ± 22,77 (p = 0,38). Mean PPOPS of 183 patients analyzed was 12,32 ± 4,96. Mean PPOPS of extruded group was 12,94 ± 4,68 and 11,92 ± 5,11 in not extruded one (p = 0,166).
E&E are suture-type sensitive (V-Loc > Stratafix), reported more frequent when BRP is performed alone than BRP-TORS with no statistical significance. 76,7% of the E&E occur after patient discharge and within 2 months. About half of the E&E were localized in soft palate. There is no need to fear Extrusion&Exposition because it does not affect in a negative way subjective and PSG outcome.
分析挤压和暴露(E&E)现象,及其对接受带刺咽成形术(BRP)治疗的阻塞性睡眠呼吸暂停(OSA)患者的功能、解剖学结果和主观不适的影响。
对 488 例接受 BRP 或多平面 TORS 治疗的患者进行研究。230 例患者使用 Stratafix 缝线,258 例患者使用 V-Loc 缝线。在随访时评估 E&E 的发生、时间和部位。多导睡眠图用于评估 E&E 对功能结果的影响,PPOPS 问卷用于评估主观不适。
在整个研究组中,E&E 的发生率为 18.4%,Stratafix 缝线与 V-Loc 缝线之间存在显著差异(p=0.002),但 BRP 单独治疗与多平面手术之间无差异(p=0.68)。28.9%的缝线挤出发生在术后 7 天内,76.7%发生在术后 7 天至 2 个月之间,5.5%发生在术后 2 个月后。62.2%的患者出现有症状的临床特征,37.8%的患者无症状。35.5%的 E&E 发生在扁桃体床,46.7%发生在软腭,20%发生在其他部位。发生 E&E 的患者的平均 delta-AHI 为-15.87±16.82,而未发生 E&E 的患者为-16.34±22.77(p=0.38)。对 183 例患者进行分析,平均 PPOPS 为 12.32±4.96。挤出组的平均 PPOPS 为 12.94±4.68,未挤出组为 11.92±5.11(p=0.166)。
E&E 与缝线类型有关(V-Loc>Stratafix),BRP 单独治疗时比 BRP-TORS 更常见,但无统计学意义。76.7%的 E&E 发生在患者出院后 2 个月内。大约一半的 E&E 发生在软腭。挤压和暴露现象并不会对主观和 PSG 结果产生负面影响,因此无需担心。