Radovanović Katarina, Gavarić Neda, Aćimović Milica
Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.
Department of Vegetable and Alternative Crops, Institute of Field and Vegetable Crops Novi Sad, Maksima Gorkog 30, 21000 Novi Sad, Serbia.
Life (Basel). 2023 Mar 24;13(4):874. doi: 10.3390/life13040874.
Inflammation is a natural protective response of the human body to a variety of hostile agents and noxious stimuli. Standard anti-inflammatory therapy includes drugs whose usage is associated with a number of side effects. Since ancient times, natural compounds have been used for the treatment of inflammation. Traditionally, the use of medicinal plants is considered safe, inexpensive, and widely acceptable. In Serbia, traditional medicine, based on the strong belief in the power of medicinal herbs, is the widespread form of treatment. This is supported by the fact that Serbia is classified as one of 158 world centers of biodiversity, which confirms that this country is a treasure of medicinal herbs. Some of the most used herbs for the treatment of inflammations of various causes in Serbian tradition are yarrow, common agrimony, couch grass, onion, garlic, marshmallow, common birch, calendula, liquorice, walnut, St. John's wort, chamomile, peppermint, white willow, sage, and many others. The biological activity and anti-inflammatory effect of selected plants are attributed to different groups of secondary biomolecules such as flavonoids, phenolic acids, sterols, terpenoids, sesquiterpenes, and tannins. This paper provides an overview of plants with traditional anti-inflammatory use in Serbia with reference to available studies that examined this effect. Plants used in traditional medicine could be a powerful source for the development of new remedies. Therefore intensive research on the bioactive potential of medicinal plants in each region should be the focus of scientists around the world.
炎症是人体对多种有害因子和有害刺激的一种自然保护反应。标准的抗炎疗法所使用的药物会产生一些副作用。自古以来，天然化合物就被用于治疗炎症。传统上，药用植物的使用被认为是安全、廉价且广泛可接受的。在塞尔维亚，基于对草药功效的坚定信念，传统医学是一种广泛应用的治疗形式。塞尔维亚被列为世界158个生物多样性中心之一，这一事实支持了上述观点，也证实了这个国家是草药的宝库。在塞尔维亚传统医学中，一些最常用于治疗各种炎症的草药有蓍草、龙牙草、匍匐冰草、洋葱、大蒜、药蜀葵、欧洲白桦、金盏花、甘草、核桃、圣约翰草、洋甘菊、薄荷、白柳树、鼠尾草等等。所选植物的生物活性和抗炎作用归因于不同类别的次生生物分子，如黄酮类、酚酸类、甾醇类、萜类、倍半萜类和单宁类。本文参考了已有的相关研究，概述了塞尔维亚传统上用于抗炎的植物。传统医学中使用的植物可能是开发新疗法的强大资源。因此，对各地区药用植物生物活性潜力的深入研究应成为世界各地科学家的重点。
