Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Cancer Cell. 2021 Mar 8;39(3):304-306. doi: 10.1016/j.ccell.2021.02.012.
The notion of the brain as an immune-privileged organ has been challenged by the discovery of functional lymphatic vessels in the meninges of the dorsal and basal skull. A study published in Nature in 2020 shows that meningeal lymphatics play an important role in the sensing of brain tumor antigens.
大脑作为免疫特权器官的概念受到了挑战,因为人们在颅背侧和颅底部脑膜中发现了功能性淋巴管。2020 年发表在《自然》杂志上的一项研究表明,脑膜淋巴管在大脑肿瘤抗原的感应中起着重要作用。