通用货币任务在转化精神病学中的重要性。
The Importance of Common Currency Tasks in Translational Psychiatry.
作者信息
Pike Alexandra C, Lowther Millie, Robinson Oliver J
机构信息
Anxiety Lab, Neuroscience and Mental Health Group, University College London Institute of Cognitive Neuroscience, Alexandra House, 17-19 Queen Square, Bloomsbury, London, WC1N 3AR UK.
Research Department of Clinical, Educational and Health Psychology Department, University College London, Gower Street, London, WC1E 6BT UK.
出版信息
Curr Behav Neurosci Rep. 2021;8(1):1-10. doi: 10.1007/s40473-021-00225-w. Epub 2021 Feb 12.
PURPOSE OF REVIEW
Common currency tasks are tasks that investigate the same phenomenon in different species. In this review, we discuss how to ensure the translational validity of common currency tasks, summarise their benefits, present recent research in this area and offer future directions and recommendations.
RECENT FINDINGS
We discuss the strengths and limitations of three specific examples where common currency tasks have added to our understanding of psychiatric constructs-affective bias, reversal learning and goal-based decision making.
SUMMARY
Overall, common currency tasks offer the potential to improve drug discovery in psychiatry. We recommend that researchers prioritise construct validity above face validity when designing common currency tasks and suggest that the evidence for construct validity is summarised in papers presenting research in this area.
综述目的
通用货币任务是指在不同物种中研究同一现象的任务。在本综述中，我们讨论了如何确保通用货币任务的转化效度，总结了它们的优点，介绍了该领域的最新研究，并提供了未来的方向和建议。
最新发现
我们讨论了通用货币任务增加了我们对精神疾病结构——情感偏差、逆向学习和基于目标的决策的理解的三个具体例子的优点和局限性。
总结
总体而言，通用货币任务为改善精神病学药物研发提供了潜力。我们建议研究人员在设计通用货币任务时，将结构效度置于表面效度之上，并建议在发表该领域研究的论文中总结结构效度的证据。
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