Farghaly Wafaa M, El Tallawy Hamdy N, Mohamed Heba, El Tallawy Sara H, Abdelhamed Mohamed A
Department of Neuropsychiatry, and Neuroepidemiology Lab, Faculty of Medicine, Assiut University, Assiut, Egypt.
Department of Psychology, Faculty of Arts, Assiut University, Assiut, Egypt.
Neuropsychiatr Dis Treat. 2021 Mar 3;17:721-729. doi: 10.2147/NDT.S291392. eCollection 2021.
Validated diagnostic scales for dementia in Arabic are still scarce. The aim of this study is to construct a standardized dementia scale for dementia diagnosis among the Arabic-speaking population.
Construction of the Dementia Arabic Scale (DAS) was done, followed by evaluation of content validity. A pilot study was done to ascertain feasibility and language clarity used in the scale. Patients diagnosed to have major neurocognitive disorder according to DSM-V criteria and control group were subjected to DAS, mini-mental state examination (MMSE) and Cognitive Abilities Screening Instrument (CASI). Finally, standardization of the scale and estimation of cutoff point, sensitivity, specificity, positive predictive value and negative predictive value of the newly constructed scale (DAS) were done.
There is significant correlation between DAS and both MMSE and CASI on Pearson's correlation study. The internal consistency of the DAS scale was good, with Cronbach's alpha correlation coefficient of 0.88. At cut-off ≤95 for literate, and ≤68 for illiterate, the sensitivity of the DAS scale was 100%, 87% for literate and illiterate, respectively, while specificity was 84%, 96% respectively, with an area under the receiver operating characteristic curve of (AUC) 0.96.
The DAS scale is an acceptable, reliable and valid scale for the diagnosis of dementia in Arabic-speaking countries.
阿拉伯语版的痴呆症有效诊断量表仍然稀缺。本研究的目的是构建一个标准化的痴呆症量表，用于在讲阿拉伯语的人群中进行痴呆症诊断。
构建了阿拉伯语痴呆量表（DAS），随后评估了内容效度。进行了一项试点研究，以确定该量表的可行性和语言清晰度。根据DSM-V标准诊断为患有重度神经认知障碍的患者和对照组接受了DAS、简易精神状态检查表（MMSE）和认知能力筛查工具（CASI）测试。最后，对该量表进行了标准化，并估计了新构建量表（DAS）的截断点、敏感性、特异性、阳性预测值和阴性预测值。
在Pearson相关性研究中，DAS与MMSE和CASI均存在显著相关性。DAS量表的内部一致性良好，Cronbach's alpha相关系数为0.88。在识字者截断值≤95、文盲截断值≤68时，DAS量表的敏感性分别为100%、识字者87%、文盲87%，而特异性分别为84%、96%，受试者工作特征曲线下面积（AUC）为0.96。
DAS量表是用于在讲阿拉伯语国家诊断痴呆症的一个可接受、可靠且有效的量表。
