Department of Radiation Oncology, School of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.
J Appl Clin Med Phys. 2021 Apr;22(4):172-183. doi: 10.1002/acm2.13170. Epub 2021 Mar 19.
Studies have evaluated the viability of using open-face masks as an immobilization technique to treat intracranial and head and neck cancers. This method offers less stress to the patient with comparable accuracy to closed-face masks. Open-face masks permit implementation of surface guided radiation therapy (SGRT) to assist in positioning and motion management. Research suggests that changes in patient facial expressions may influence the SGRT system to generate false positional corrections. This study aims to quantify these errors produced by the SGRT system due to face motion.
Ten human subjects were immobilized using open-face masks. Four discrete SGRT regions of interest (ROIs) were analyzed based on anatomical features to simulate different mask openings. The largest ROI was lateral to the cheeks, superior to the eyebrows, and inferior to the mouth. The smallest ROI included only the eyes and bridge of the nose. Subjects were asked to open and close their eyes and simulate fear and annoyance and peak isocenter shifts were recorded. This was performed in both standard and SRS specific resolutions with the C-RAD Catalyst HD system.
All four ROIs analyzed in SRS and Standard resolutions demonstrated an average deviation of 0.3 ± 0.3 mm for eyes closed and 0.4 ± 0.4 mm shift for eyes open, and 0.3 ± 0.3 mm for eyes closed and 0.8 ± 0.9 mm shift for eyes open. The average deviation observed due to changing facial expressions was 1.4 ± 0.9 mm for SRS specific and 1.6 ± 1.6 mm for standard resolution.
The SGRT system can generate false positional corrections for face motion and this is amplified at lower resolutions and smaller ROIs. These errors should be considered in the overall tolerances and treatment plan when using open-face masks with SGRT and may warrant additional radiographic imaging.
已有研究评估了使用开放式面罩作为颅内和头颈部癌症治疗的固定技术的可行性。这种方法对患者的压力较小,准确性与封闭式面罩相当。开放式面罩允许实施表面引导放射治疗(SGRT)以辅助定位和运动管理。研究表明,患者面部表情的变化可能会影响 SGRT 系统生成错误的位置校正。本研究旨在量化由于面部运动而导致 SGRT 系统产生的这些误差。
使用开放式面罩对 10 名人体受检者进行固定。根据解剖特征分析了四个离散的 SGRT 感兴趣区(ROI),以模拟不同的面罩开口。最大 ROI 位于脸颊外侧、眉毛上方和嘴部下方。最小 ROI 仅包括眼睛和鼻梁。要求受检者睁开和闭上眼睛,并模拟恐惧和恼怒,记录峰值等中心点的移位。在 C-RAD Catalyst HD 系统中以标准和 SRS 特定分辨率进行了此操作。
在 SRS 和标准分辨率下分析的所有四个 ROI 在闭眼时平均偏差为 0.3±0.3mm,睁眼时为 0.4±0.4mm,闭眼时为 0.3±0.3mm,睁眼时为 0.8±0.9mm。由于面部表情变化而观察到的平均偏差在 SRS 特定分辨率下为 1.4±0.9mm,在标准分辨率下为 1.6±1.6mm。
SGRT 系统会对面部运动产生错误的位置校正,而在较低分辨率和较小 ROI 下,这种校正会被放大。在使用带有 SGRT 的开放式面罩时,这些误差应考虑在总容差和治疗计划中,并且可能需要额外的放射影像学检查。