Department of Women's and Children's Health, Uppsala University, Akademiska sjukhuset, SE-751 85, Uppsala, Sweden.
Karolinska Institutet, Department of Global Public Health, K9 Global folkhälsa, K9 GH Stålsby Lundborg Hanson, SE-171 77, Stockholm, Sweden.
BMC Public Health. 2021 Mar 20;21(1):552. doi: 10.1186/s12889-021-10583-5.
The resurgence of measles globally and the increasing number of unvaccinated clusters call for studies exploring factors that influence measles vaccination uptake. Armenia is a middle-income post-Soviet country with an officially high vaccination coverage. However, concerns about vaccine safety are common. The purpose of this study was to measure the prevalence of measles vaccination coverage in children under three years of age and to identify factors that are associated with measles vaccination in Armenia by using nationally representative data.
Cross-sectional analysis using self-report data from the most recent Armenian Demographic Health Survey (ADHS VII 2015/16) was conducted. Among 588 eligible women with a last-born child aged 12-35 months, 63 women were excluded due to unknown status of measles vaccination, resulting in 525 women included in the final analyses. We used logistic regression models in order to identify factors associated with vaccination status in the final sample. Complex sample analyses were used to account for the study design.
In the studied population 79.6% of the children were vaccinated against measles. After adjusting for potential confounders, regression models showed that the increasing age of the child (AOR 1.07, 95% CI: 1.03-1.12), secondary education of the mothers (AOR 3.38, 95% CI: 1.17-9.76) and attendance at postnatal check-up within two months after birth (AOR 2.71, 95% CI: 1.17-6.30) were significantly associated with the vaccination status of the child.
The measles vaccination coverage among the children was lower than the recommended percentage. The study confirmed the importance of maternal education and attending postnatal care visits. However, the study also showed that there might be potential risks for future measles outbreaks because of delayed vaccinations and a large group of children with an unknown vaccination status.
麻疹在全球范围内死灰复燃，未接种疫苗的聚集性病例不断增加，这促使人们开展研究，以探索影响麻疹疫苗接种率的因素。亚美尼亚是一个中等收入的前苏联国家，官方报告的疫苗接种率较高。然而，人们普遍对疫苗安全性感到担忧。本研究旨在通过使用全国代表性数据，衡量亚美尼亚三岁以下儿童麻疹疫苗接种的覆盖率，并确定与麻疹疫苗接种相关的因素。
本研究采用横断面分析，使用最近一次亚美尼亚人口健康调查（ADHS VII 2015/16）的自我报告数据。在 588 名最后一个出生的孩子年龄在 12-35 个月之间的合格妇女中，有 63 名妇女因麻疹疫苗接种状况未知而被排除在外，最终有 525 名妇女纳入最终分析。我们使用逻辑回归模型来确定最终样本中与接种状况相关的因素。采用复杂样本分析来考虑研究设计。
在所研究的人群中，79.6%的儿童接种了麻疹疫苗。在校正潜在混杂因素后，回归模型显示，儿童年龄的增加（AOR 1.07，95%CI：1.03-1.12）、母亲的中等教育程度（AOR 3.38，95%CI：1.17-9.76）和在出生后两个月内进行产后检查（AOR 2.71，95%CI：1.17-6.30）与儿童的接种状况显著相关。
儿童的麻疹疫苗接种覆盖率低于推荐的百分比。该研究证实了母亲教育和接受产后护理的重要性。然而，研究还表明，由于疫苗接种延迟和大量儿童疫苗接种状况未知，未来可能存在麻疹爆发的潜在风险。
