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克里米亚-刚果出血热病毒(CCHFV):一种隐匿却广泛存在的威胁。

Crimean-Congo Hemorrhagic Fever Virus (CCHFV): A Silent but Widespread Threat.

作者信息

Kuehnert Paul A, Stefan Christopher P, Badger Catherine V, Ricks Keersten M

机构信息

Diagnostic Systems Division, US Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Frederick, MD 21702 USA.

Virology Division, US Army Medical Research Institute of Infectious Diseases, 1425 Porter St, Frederick, MD 21702 USA.

出版信息

Curr Trop Med Rep. 2021;8(2):141-147. doi: 10.1007/s40475-021-00235-4. Epub 2021 Mar 16.

Abstract

PURPOSE OF REVIEW

This review is aimed at highlighting recent research and articles on the complicated relationship between virus, vector, and host and how biosurveillance at each level informs disease spread and risk.

RECENT FINDINGS

While human cases of CCHFV and tick identification in non-endemic areas in 2019-2020 were reported to sites such as ProMed, there is a gap in recent published literature on these and broader CCHFV surveillance efforts from the late 2010s.

SUMMARY

A review of the complex aspects of CCHFV maintenance in the environment coupled with high fatality rate and lack of vaccines and therapeutics warrants the need for a One-Health approach toward detection and increased biosurveillance programs for CCHFV.

摘要

综述目的

本综述旨在突出近期关于病毒、媒介和宿主之间复杂关系的研究及文章,以及各级生物监测如何为疾病传播和风险提供信息。

最新发现

虽然2019 - 2020年在非流行地区的人类克里米亚-刚果出血热病毒(CCHFV)病例和蜱虫鉴定情况已报告给了如ProMed等机构,但自2010年代后期以来,关于这些以及更广泛的CCHFV监测工作的近期发表文献存在空白。

总结

鉴于CCHFV在环境中维持的复杂情况、高死亡率以及缺乏疫苗和治疗方法,有必要采取“同一健康”方法来检测CCHFV并加强其生物监测计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a1f/7959879/4f8fd37e7140/40475_2021_235_Fig1_HTML.jpg

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