Centre for Evidence Based Hand Surgery, School of Medicine, University of Nottingham, Nottingham, UK.
Trauma and Orthopaedics, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom, UK.
BMJ Open. 2021 Mar 26;11(3):e044207. doi: 10.1136/bmjopen-2020-044207.
Prioritisation of important treatment uncertainties for 'Common Conditions Affecting the Hand and Wrist' via a UK-based James Lind Alliance Priority Setting Partnership.
This process was funded by a national charitable organisation and based in the UK.
Anyone with experience of common conditions affecting the adult hand and wrist, including patients, carers and healthcare professionals. All treatment modalities delivered by a hand specialist, including therapists, surgeons or other allied professionals, were considered.
Established James Lind Alliance Priority Setting Partnership methods were employed.Electronic and paper questionnaires identified potential uncertainties. These were subsequently confirmed using relevant, up-to-date systematic reviews. A final list of top 10 research uncertainties was developed via a face-to-face workshop with representation from patients and clinicians. Impact of research was sought by surveying hand clinicians electronically.
The survey responses and prioritisation-both survey and workshop based.
There were 889 individually submitted questions from the initial survey, refined to 59 uncertainties across 32 themes. Eight additional uncertainties were added from published literature before prioritisation by 261 participants and the workshop allowed the final top 10 list to be finalised. The top 10 has so far contributed to the award of over £3.8 million of competitively awarded funding.
The Common Conditions in the Hand and Wrist Priority Setting Partnership identified important research questions and has allowed research funders to identify grant applications which are important to both patients and clinicians.
通过英国詹姆斯林德联盟优先设置伙伴关系，确定“影响手和腕部的常见疾病”的重要治疗不确定性。
该过程由一个国家慈善组织资助，总部设在英国。
任何对手部和腕部常见疾病有经验的人，包括患者、护理人员和医疗保健专业人员。所有由手部专家提供的治疗方式，包括治疗师、外科医生或其他相关专业人员，都被考虑在内。
采用了既定的詹姆斯林德联盟优先设置伙伴关系方法。电子和纸质问卷确定了潜在的不确定性。随后使用相关的最新系统评价对其进行了确认。通过患者和临床医生代表参加的面对面研讨会，制定了最终的十大研究不确定性清单。通过电子方式向手部临床医生调查研究的影响。
调查回复和基于调查和研讨会的优先级排序。
初始调查收到了 889 条单独提交的问题，经过精炼后确定了 59 个涉及 32 个主题的不确定性。在 261 名参与者进行优先级排序之前，从已发表的文献中又增加了 8 个不确定性，然后通过研讨会确定了最终的前 10 名。迄今为止，前 10 名已经促成了超过 380 万英镑的竞争性拨款。
手部常见疾病优先设置伙伴关系确定了重要的研究问题，并使研究资助者能够确定对患者和临床医生都重要的拨款申请。
