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疫情封锁期间沙特室内灰尘中的多环芳烃:现状、来源及对人类健康的危害

Polycyclic Aromatic Hydrocarbons in Indoor Dust Collected during the COVID-19 Pandemic Lockdown in Saudi Arabia: Status, Sources and Human Health Risks.

机构信息

Department of Family Medicine, Medical College, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

Centre of Excellence in Environmental Studies, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

出版信息

Int J Environ Res Public Health. 2021 Mar 8;18(5):2743. doi: 10.3390/ijerph18052743.

DOI:10.3390/ijerph18052743
PMID:33800440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7967472/
Abstract

To control the spread of coronavirus disease (COVID-19), Saudi Arabia's government imposed a strict lockdown during March-July 2020. As a result, the public was confined to indoors, and most of their daily activities were happening in their indoor places, which might have resulted in lower indoor environment quality. Polycyclic aromatic hydrocarbons (PAHs) were analyzed in household dust ( = 40) collected from different residential districts of Jeddah, Saudi Arabia, during the lockdown period. PAHs' levels were two folds higher than the previously reported PAHs in indoor dust from this region. We detected low molecular weight (LMW) with two to four aromatic ring PAHs in all the samples with a significant contribution from Phenanthrene (Phe), present at an average concentration of 1590 ng/g of dust. Although high molecular weight (HMW) (5-6 aromatic ring) PAHs were detected at lower concentrations than LMW PAHs, however, they contributed >90% in the carcinogenic index of PAHs. The estimated daily intake (EDI) of specific PAHs was above the reference dose (RfD) for young children in high-end exposure and the calculated Incremental Lifetime Cancer Risk (ILCR) was >1.00 × 10 for both Saudi adults and young children. The study highlighted that indoor pollution has increased significantly during lockdown due to the increased indoor activities and inversely affect human health. This study also warrants to conduct more studies involving different chemicals to understand the indoor environment quality during strict lockdown conditions.

摘要

为控制 2020 年 3 月至 7 月期间的冠状病毒病(COVID-19)的传播,沙特阿拉伯政府实施了严格的封锁。因此,公众被限制在室内,他们的大部分日常活动都在室内进行,这可能导致室内环境质量下降。对沙特阿拉伯吉达不同住宅区在封锁期间收集的家庭灰尘(= 40)进行了多环芳烃(PAHs)分析。PAHs 的水平比该地区以前报告的室内灰尘中的 PAHs 高出两倍。我们在所有样本中均检测到低分子量(LMW)和具有两个至四个芳香环的 PAHs,其中菲(Phe)的贡献显著,其平均浓度为 1590ng/g 灰尘。尽管高分子量(HMW)(5-6 个芳香环)PAHs 的浓度低于 LMW PAHs,但它们在 PAHs 的致癌指数中占比>90%。特定 PAHs 的估计每日摄入量(EDI)在高暴露的儿童参考剂量(RfD)之上,计算出的沙特成年人和儿童的终生癌症风险增量(ILCR)均>1.00×10。该研究强调,由于室内活动的增加,室内污染在封锁期间显著增加,从而对人类健康产生负面影响。本研究还需要进行更多涉及不同化学物质的研究,以了解严格封锁条件下的室内环境质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a82f/7967472/393fa0df9d4c/ijerph-18-02743-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a82f/7967472/247cac48b37e/ijerph-18-02743-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a82f/7967472/393fa0df9d4c/ijerph-18-02743-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a82f/7967472/247cac48b37e/ijerph-18-02743-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a82f/7967472/393fa0df9d4c/ijerph-18-02743-g002.jpg

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