神经损伤与再生模型。
, and Models for Peripheral Nerve Injury and Regeneration.
机构信息
Hand and Microsurgery, Division of Plastic Surgery, Department of Surgery, School of Medicine, University of California Davis, Sacramento, California, USA.
Department of Surgery, School of Medicine, University of California Davis, Sacramento, California, USA.
出版信息
Curr Neuropharmacol. 2022;20(2):344-361. doi: 10.2174/1570159X19666210407155543.
Abstract
Peripheral Nerve Injuries (PNI) frequently occur secondary to traumatic injuries. Recovery from these injuries can be expectedly poor, especially in proximal injuries. In order to study and improve peripheral nerve regeneration, scientists rely on peripheral nerve models to identify and test therapeutic interventions. In this review, we discuss the best described and most commonly used peripheral nerve models that scientists have and continue to use to study peripheral nerve physiology and function.
摘要
周围神经损伤（PNI）常继发于创伤。这些损伤的恢复通常较差，尤其是在近端损伤时。为了研究和改善周围神经再生，科学家们依赖于周围神经模型来识别和测试治疗干预措施。在这篇综述中，我们讨论了科学家们已经使用并继续使用的描述最好、最常用的周围神经模型，以研究周围神经的生理学和功能。
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