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苏丹北部成年糖尿病患者高血压患病率及相关因素的横断面研究。

Prevalence and associated factors of hypertension among adults with diabetes mellitus in northern Sudan: a cross-sectional study.

机构信息

Department of Pathology, Qunfudah Medical college, Umm-Al-Qura University, Al-Qunfudah, Kingdom of Saudi Arabia.

Department of Medicine, Royal Commission Hospital, Jubail Industrial City, Al Jubail, Kingdom of Saudi Arabia.

出版信息

BMC Cardiovasc Disord. 2021 Apr 10;21(1):168. doi: 10.1186/s12872-021-01983-x.

DOI:10.1186/s12872-021-01983-x
PMID:33838664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8037914/
Abstract

BACKGROUND

Hypertension and diabetes mellitus (DM), are highly prevalent worldwide health non-communicable diseases, and are associated with chronic complications. The co-existence of both conditions accelerates the related complications and increases morbidities and mortalities. A cross-sectional study was conducted in Nahr an Nil State (River Nile State) in Sudan between May and August 2018 to identify the prevalence of hypertension and risk factors among patients with DM in that region.

RESULTS

The median (interquartile) age of the 1,973 enrolled patients was 58.0 (50.0‒65.0) years, and 818 (45.6%) were males. The median (interquartile) duration of diabetes was 5.0 (3.0‒9.0) years. Of the 1,973 enrolled participants, 21.7%, 1.3%, 37.1%, and 39.9% were normal weight, underweight, overweight, and obese, respectively. Of 1,973 854 (47.6%) patients also had hypertension. Logistic regression analyses showed that elderly patients (adjusted odds ratio [AOR] = 1.03, 95%; confidence interval [CI] = 1.02‒1.04), males (AOR = 2.96, 95%; CI = 2.15‒4.07), employed patients (AOR = 1.92, 95%; CI = 1.38‒2.70), obese patients (AOR = 1.59, 95%; CI = 1.21‒2.08), and patients with diabetic foot (DF) (AOR = 2.45, 95%; CI = 1.72‒3.47) were at higher risk for hypertension. Conversely, patients with Type 2 DM (T2DM) (AOR = 0.63, 95%; CI = 0.50‒0.80) were at lower risk for hypertension. There was no significant association between overweight, uncontrolled DM, and hypertension.

CONCLUSION

This study showed a high prevalence of hypertension among patients with DM. Notably, older age, male gender, employment, duration of DM, DF, underweight, and obesity were significant predictors of hypertension among patients with DM.

摘要

背景

高血压和糖尿病(DM)是全球普遍存在的非传染性健康疾病,与慢性并发症有关。这两种疾病同时存在会加速相关并发症的发生,并增加发病率和死亡率。2018 年 5 月至 8 月,在苏丹的 Nahr an Nil 州(尼罗河州)进行了一项横断面研究,旨在确定该地区 DM 患者的高血压患病率及其危险因素。

结果

纳入的 1973 名患者的中位(四分位间距)年龄为 58.0(50.0-65.0)岁,818 名(45.6%)为男性。糖尿病的中位(四分位间距)病程为 5.0(3.0-9.0)年。在纳入的 1973 名参与者中,分别有 21.7%、1.3%、37.1%和 39.9%为正常体重、体重不足、超重和肥胖。在 1973 名患者中,有 854 名(47.6%)患有高血压。逻辑回归分析显示,老年患者(调整后的优势比[OR] = 1.03,95%;置信区间[CI] = 1.02-1.04)、男性(OR = 2.96,95%;CI = 2.15-4.07)、在职患者(OR = 1.92,95%;CI = 1.38-2.70)、肥胖患者(OR = 1.59,95%;CI = 1.21-2.08)和患有糖尿病足(DF)的患者(OR = 2.45,95%;CI = 1.72-3.47)患高血压的风险更高。相反,2 型糖尿病(T2DM)患者(OR = 0.63,95%;CI = 0.50-0.80)患高血压的风险较低。超重、DM 控制不佳与高血压之间无显著关联。

结论

本研究显示,DM 患者中高血压的患病率较高。值得注意的是,年龄较大、男性、就业、DM 病程、DF、体重不足和肥胖是 DM 患者高血压的显著预测因素。