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通过经颅电刺激研究神经振荡因果作用的综合方法。

Toward integrative approaches to study the causal role of neural oscillations via transcranial electrical stimulation.

机构信息

Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.

Neuroscience Center Zurich, Switzerland, Zurich, Switzerland.

出版信息

Nat Commun. 2021 Apr 14;12(1):2243. doi: 10.1038/s41467-021-22468-7.

Abstract

Diverse transcranial electrical stimulation (tES) techniques have recently been developed to elucidate the role of neural oscillations, but critically, it remains questionable whether neural entrainment genuinely occurs and is causally related to the resulting behavior. Here, we provide a perspective on an emerging integrative research program across systems, species, theoretical and experimental frameworks to elucidate the potential of tES to induce neural entrainment. We argue that such an integrative agenda is a requirement to establish tES as a tool to test the causal role of neural oscillations and highlight critical issues that should be considered when adopting a translational approach.

摘要

多种经颅电刺激 (tES) 技术最近已经被开发出来,以阐明神经振荡的作用,但关键问题是,神经节律确实发生并且与所产生的行为有因果关系仍然值得怀疑。在这里,我们提供了一个跨系统、跨物种、理论和实验框架的新兴综合研究计划的视角,以阐明 tES 诱导神经节律的潜力。我们认为,这种综合方案是将 tES 确立为测试神经振荡因果作用的工具的必要条件,并强调了在采用转化方法时应该考虑的关键问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd3e/8047004/7eccb85bf525/41467_2021_22468_Fig1_HTML.jpg

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