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一个 compartmental model 预测社交距离和疫苗接种对控制 COVID-19 的影响。

A compartmental model that predicts the effect of social distancing and vaccination on controlling COVID-19.

机构信息

Department of Applied Mathematics, Faculty of Mathematical Sciences, Tarbiat Modares University, Jalal Al-Ahmad High Way, Tehran, Iran.

出版信息

Sci Rep. 2021 Apr 14;11(1):8191. doi: 10.1038/s41598-021-86873-0.

Abstract

The understanding of the interaction between disease dynamics and human behavior is an important and essential point to control infectious. Disease outbreak can be influenced by social distancing and vaccination. In this study, we introduce two compartmental models to derive the epidemic curve and analyze the individual's behavior in spreading and controlling the COVID-19 epidemic. The first model includes Susceptible, Exposed, Infectious, Hospitalized, Recovered and Death compartments and in the second model, we added a new compartment namely, semi-susceptible individuals that are assumed to be more immune than the susceptible. A comparison of the two models shows that the second model provides a better fit to the daily infected cases from Egypt, Belgium, Japan, Nigeria, Italy, and Germany released by WHO. Finally, we added a vaccinated term to the model to predict how vaccination could control the epidemic. The model was applied on the record data from WHO.

摘要

理解疾病动态和人类行为之间的相互作用是控制传染病的一个重要和必要的关键点。疾病爆发可以通过社交距离和疫苗接种来影响。在这项研究中,我们引入了两个隔室模型来推导出流行曲线,并分析个体在传播和控制 COVID-19 疫情中的行为。第一个模型包括易感者、暴露者、感染者、住院者、康复者和死亡者隔室,而在第二个模型中,我们添加了一个新的隔室,即半易感者,他们被认为比易感者更有免疫力。对两个模型的比较表明,第二个模型更能拟合世界卫生组织公布的来自埃及、比利时、日本、尼日利亚、意大利和德国的每日感染病例。最后,我们在模型中添加了一个接种疫苗的术语来预测疫苗接种如何控制疫情。该模型应用于世界卫生组织的记录数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a76/8046797/18bbbd011305/41598_2021_86873_Fig1_HTML.jpg

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