IEEE Trans Neural Netw Learn Syst. 2021 May;32(5):1810-1820. doi: 10.1109/TNNLS.2021.3070467. Epub 2021 May 3.
Coronavirus disease (COVID-19) has been the main agenda of the whole world ever since it came into sight. X-ray imaging is a common and easily accessible tool that has great potential for COVID-19 diagnosis and prognosis. Deep learning techniques can generally provide state-of-the-art performance in many classification tasks when trained properly over large data sets. However, data scarcity can be a crucial obstacle when using them for COVID-19 detection. Alternative approaches such as representation-based classification [collaborative or sparse representation (SR)] might provide satisfactory performance with limited size data sets, but they generally fall short in performance or speed compared to the neural network (NN)-based methods. To address this deficiency, convolution support estimation network (CSEN) has recently been proposed as a bridge between representation-based and NN approaches by providing a noniterative real-time mapping from query sample to ideally SR coefficient support, which is critical information for class decision in representation-based techniques. The main premises of this study can be summarized as follows: 1) A benchmark X-ray data set, namely QaTa-Cov19, containing over 6200 X-ray images is created. The data set covering 462 X-ray images from COVID-19 patients along with three other classes; bacterial pneumonia, viral pneumonia, and normal. 2) The proposed CSEN-based classification scheme equipped with feature extraction from state-of-the-art deep NN solution for X-ray images, CheXNet, achieves over 98% sensitivity and over 95% specificity for COVID-19 recognition directly from raw X-ray images when the average performance of 5-fold cross validation over QaTa-Cov19 data set is calculated. 3) Having such an elegant COVID-19 assistive diagnosis performance, this study further provides evidence that COVID-19 induces a unique pattern in X-rays that can be discriminated with high accuracy.
冠状病毒病 (COVID-19) 自出现以来一直是全世界的主要议题。X 射线成像是一种常见且易于获取的工具,对于 COVID-19 的诊断和预后具有很大的潜力。深度学习技术在经过大量数据集的适当训练后,通常可以在许多分类任务中提供最先进的性能。然而,数据稀缺可能是使用它们进行 COVID-19 检测的关键障碍。替代方法,如基于表示的分类 [协作或稀疏表示 (SR)],在使用有限大小的数据集时可能会提供令人满意的性能,但与基于神经网络 (NN) 的方法相比,它们的性能或速度通常较差。为了解决这个不足,卷积支撑估计网络 (CSEN) 最近被提出作为基于表示和 NN 方法之间的桥梁,通过提供从查询样本到理想 SR 系数支撑的非迭代实时映射,这是基于表示的技术中分类决策的关键信息。本研究的主要前提可以概括如下:1)创建了一个名为 QaTa-Cov19 的基准 X 射线数据集,其中包含超过 6200 张 X 射线图像。该数据集涵盖了来自 COVID-19 患者的 462 张 X 射线图像以及另外三个类别:细菌性肺炎、病毒性肺炎和正常。2)基于 CSEN 的分类方案配备了用于 X 射线图像的最先进的深度 NN 解决方案 CheXNet 的特征提取,当计算 QaTa-Cov19 数据集的 5 倍交叉验证的平均性能时,直接从原始 X 射线图像中,COVID-19 的识别率超过 98%,特异性超过 95%。3)具有如此优雅的 COVID-19 辅助诊断性能,本研究进一步证明 COVID-19 在 X 射线中诱导出一种独特的模式,可以高精度地识别。