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维生素 D 及其受体在口腔扁平苔藓中的作用:系统评价。

Role of Vitamin D and Vitamin D Receptor in Oral Lichen Planus: A Systematic Review.

机构信息

Assistant Professor, Department of Oral Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

Assistant Professor, Department of Restorative Dentistry, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Ethiop J Health Sci. 2020 Jul 1;30(4):615-622. doi: 10.4314/ejhs.v30i4.17.

Abstract

BACKGROUND

Oral lichen planus (OLP) is known to be a chronic inflammatory disease associated with various other systemic disorders. Studies have shown that vitamin D deficiency can be involved in the pathogenesis of lichen planus. The aim of this study was to investigate the role of vitamin D and vitamin D receptor in OLP.

METHODS

In this review study, all English and Persian articles were searched by relevant keywords from the Google scholar, PubMed, science direct, Cochrane, Scopus and Sid databases until January 2020.

RESULTS

From the 16 articles obtained after reviewing the abstracts, finally 14 appropriate articles were included in this study.

CONCLUSION

According to the results of the studies, vitamin D deficiency may be associated with an increased risk of OLP lesions.

摘要

背景

口腔扁平苔藓(OLP)是一种已知的慢性炎症性疾病,与各种其他系统性疾病有关。研究表明,维生素 D 缺乏可能与扁平苔藓的发病机制有关。本研究旨在探讨维生素 D 和维生素 D 受体在 OLP 中的作用。

方法

在这项综述研究中,通过相关关键字在 Google 学术、PubMed、ScienceDirect、Cochrane、Scopus 和 Sid 数据库中搜索了所有英文和波斯语的文章,检索时间截至 2020 年 1 月。

结果

在审查摘要后获得的 16 篇文章中,最终有 14 篇合适的文章被纳入本研究。

结论

根据研究结果,维生素 D 缺乏可能与 OLP 病变的风险增加有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8ad/8054464/3acbf419cd8a/EJHS3004-0615Fig1.jpg

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