Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hong Kong Special Administrative Region, China.
Ciechanover Institute of Precision and Regenerative Medicine, The Chinese University of Hong Kong (Shenzhen), Shenzhen, China.
Crit Rev Food Sci Nutr. 2022;62(26):7319-7335. doi: 10.1080/10408398.2021.1913569. Epub 2021 Apr 27.
Quercetin is a flavonoid present in a wide variety of plant resources. Over the years, extensive efforts have been devoted to examining the potential biological effects of quercetin and to manipulating the chemical and physical properties of the flavonoid. However, limited studies have reviewed the opportunities and challenges of using quercetin in the development of functional foods. To address this necessity, in this review; we foremost present an overview of the chemical properties and stability of quercetin in food products followed by a detailed discussion of various strategies that enhance its oral bioavailability. We further highlight the areas to be practically considered during development of quercetin-based functional foods. By revisiting the current status of applied research on quercetin, it is anticipated that useful insights enabling research on quercetin can be potentially translated into practical applications in food product development.
槲皮素是一种广泛存在于各种植物资源中的类黄酮。多年来,人们一直在努力研究槲皮素的潜在生物学效应,并对类黄酮的化学和物理性质进行了调控。然而,目前仅有少量研究综述了在功能性食品开发中使用槲皮素的机遇和挑战。为了满足这一需求,在本综述中,我们首先概述了槲皮素在食品中的化学性质和稳定性,然后详细讨论了提高其口服生物利用度的各种策略。我们还强调了在开发基于槲皮素的功能性食品时需要实际考虑的领域。通过重新审视槲皮素应用研究的现状,我们期望能够为基于槲皮素的研究提供有用的见解,并将其转化为食品产品开发中的实际应用。