The Institute of Population Health Sciences (IPHS), Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Yvonne Carter Building, 58 Turner Street, London, E1 2AB, UK.
African Institute for Development Policy (AFIDEP), P.O Box 31024, Lilongwe, Malawi.
Syst Rev. 2021 Apr 27;10(1):125. doi: 10.1186/s13643-021-01680-y.
Adolescent substance use continues to be a growing major public health concern in Africa. Recent studies infer an overall estimated prevalence of 42% among adolescents in sub-Saharan Africa. Unfortunately, this phenomenon is not adequately documented across many settings in the continent despite known negative health and social consequences on affected individuals and their communities. Little is known about the social context of substance use in Africa among this population. Our aim is to conduct a systematic review, exploring the determinants and associated factors that influence adolescent substance use in Africa.
We will search the following databases (from January 2000 onwards): PubMed, the Cochrane Library, African Journals Online (AJOL), Google Scholar, ScienceDirect and the World Health Organization (WHO) African Index Medicus. We will include population-based observational studies reporting on determinants and/or risk factors of substance use among adolescents (age 10-19 years) across Africa. Two reviewers will independently screen all citations, full-text articles and abstract data. Potential conflicts will be resolved through discussion. Study methodological quality (or bias) will be appraised using appropriate tools. If feasible, we will conduct a random-effects meta-analysis of data. We plan to conduct a meta-synthesis of qualitative studies where appropriate DISCUSSION: This review will describe the range of determinants and associated factors found to significantly influence adolescent substance use in Africa over the last two decades. Documenting this evidence is important as it can potentially inform comprehensive interventions and treatment programmes that are targeted at adolescents and their parents in these settings.
PROSPERO CRD42020190158.
青少年物质使用在非洲仍是一个日益严重的主要公共卫生问题。最近的研究推断，撒哈拉以南非洲地区青少年的总体估计患病率为 42%。不幸的是，尽管已知对受影响个人及其社区有负面的健康和社会后果，但该现象在非洲大陆的许多环境中并未得到充分记录。人们对该人群在非洲的物质使用的社会背景知之甚少。我们的目的是进行系统评价，探索影响非洲青少年物质使用的决定因素和相关因素。
我们将从 2000 年 1 月开始搜索以下数据库：PubMed、Cochrane 图书馆、非洲期刊在线 (AJOL)、Google Scholar、ScienceDirect 和世界卫生组织 (WHO) 非洲医学索引。我们将包括基于人群的观察性研究，报告非洲青少年（10-19 岁）物质使用的决定因素和/或风险因素。两名评审员将独立筛选所有引文、全文文章和摘要数据。潜在的冲突将通过讨论解决。将使用适当的工具评估研究方法学质量（或偏倚）。如果可行，我们将对数据进行随机效应荟萃分析。我们计划在适当的情况下对定性研究进行元综合。
本综述将描述过去二十年中发现的对非洲青少年物质使用有重大影响的一系列决定因素和相关因素。记录这些证据很重要，因为它可以为这些环境中的青少年及其父母提供有针对性的综合干预和治疗计划提供信息。
PROSPERO CRD42020190158。
