美国天然精神香烟的综合化学特征分析
Comprehensive Chemical Characterization of Natural American Spirit Cigarettes.
作者信息
Jain Vipin, Alcheva Aleksandra, Huang Darlene, Caruso Rosalie, Jain Anshu, Lay Mula, O'Connor Richard, Stepanov Irina
机构信息
Vipin Jain, Research Associate, Masonic Cancer Center, University of Minnesota, Minneapolis, MN. Aleksandra Alcheva, Graduate Student, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN. Darlene Huang, Senior Associate, O'Neill Institute for National and Global Health Law, Georgetown University Law Center, Washington, DC. Rosalie Caruso, Senior Research Associate, Tobacco Research Laboratory, Roswell Park Comprehensive Cancer Center, Buffalo, NY. Anshu Jain, Research Scientist, Masonic Cancer Center, University of Minnesota, Minneapolis, MN. Mula Lay, Student Intern, Masonic Cancer Center, University of Minnesota, Minneapolis, MN. Richard O'Connor, Professor, Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY. Irina Stepanov, Associate Professor, Masonic Cancer Center and Division of Environmental Health Sciences, University of Minnesota, Minneapolis, MN.
出版信息
Tob Regul Sci. 2019 Jul;5(4):381-399. doi: 10.18001/trs.5.4.8.
OBJECTIVES
Marketing of the Natural American Spirit (NAS) cigarettes implies reduced risk of toxic exposures. We aimed to provide a comprehensive chemical characterization of these cigarettes.
METHODS
We analyzed 13 varieties of NAS for a range of tobacco- and combustion-derived constituents. Cigarettes were smoked by 2 standard regimens and analyzed using our routine analytical procedures. We also analyzed tobacco filler and physical cigarette characteristics.
RESULTS
Under intense smoking conditions, nicotine in smoke of NAS cigarettes averaged 3.3(±0.7) mg/cigarette, compared to 2.4(±0.4) in other brands. The levels of carcinogenic nitrosamines NNN and NNK varied extensively across NAS varieties, their sum ranging from 71 to 443 ng/cigarette. Levels of volatile toxicants were generally similar to, or higher than those found in other commercial US cigarettes.
CONCLUSIONS
High nicotine content suggests that NAS cigarettes may be more addictive than many other brands. Similarly low TSNA levels were measured in some NAS varieties, independent of whether or not they were labeled as organic. Levels of other toxicants were similar to other brands. Consumer education and additional regulatory measures are needed to address the misperceptions that NAS cigarettes are safer than other commercial cigarette brands.
目的
美国精神（NAS）牌香烟的营销暗示其有毒暴露风险较低。我们旨在对这些香烟进行全面的化学特征分析。
方法
我们分析了13种NAS香烟，检测一系列烟草及燃烧产生的成分。香烟按照2种标准方案吸食，并使用我们的常规分析程序进行分析。我们还分析了烟草填充物和香烟的物理特性。
结果
在高强度吸烟条件下，NAS香烟烟雾中的尼古丁平均含量为3.3（±0.7）毫克/支，而其他品牌为2.4（±0.4）毫克/支。致癌亚硝胺NNN和NNK的含量在不同NAS品种中差异很大，其总量在71至443纳克/支之间。挥发性毒物的含量通常与美国其他商业香烟相当，或更高。
结论
高尼古丁含量表明NAS香烟可能比许多其他品牌更容易使人上瘾。在一些NAS品种中也检测到了同样低的烟草特有亚硝胺水平，无论它们是否被标注为有机香烟。其他毒物的含量与其他品牌相似。需要开展消费者教育并采取更多监管措施，以消除人们认为NAS香烟比其他商业香烟品牌更安全的误解。
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