Tibpromma Saowaluck, Zhang Lu, Karunarathna Samantha C, Du Tian-Ye, Phukhamsakda Chayanard, Rachakunta Munikishore, Suwannarach Nakarin, Xu Jianchu, Mortimer Peter E, Wang Yue-Hu
CAS Key Laboratory for Plant Diversity and Biogeography of East Asia, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
World Agroforestry Centre, East and Central Asia, Kunming 650201, China.
Life (Basel). 2021 Apr 19;11(4):363. doi: 10.3390/life11040363.
Algae, bacteria, and fungi, as well as higher plants, produce a wide variety of secondary metabolites known as natural products. Natural products are well known as remarkable sources of many therapeutic agents. The genus is a wood-decaying fungus that belongs to family Xylariaceae. is often found as an endophyte in diverse hosts and some species are known to produce useful secondary metabolites. In this study, two species were isolated as an endophytic fungus from . Multi-gene phylogenetic studies showed that the newly described strains of are new to science, and this is the first report of from the host . One of the fermented species, (KUMCC 20-0268), resulted in five sesquiterpenoids, which were previously reported from agarwood, and their structures were identified by gas chromatography-mass spectrometry (GC-MS). In addition, five different media were investigated in vitro to optimize conditions for growing the fungal biomass of and .
藻类、细菌、真菌以及高等植物都会产生各种各样被称为天然产物的次生代谢产物。天然产物是许多治疗药物的重要来源，这是众所周知的。该属是一种属于炭角菌科的木材腐朽真菌。它常作为内生菌存在于多种宿主中，并且已知一些物种会产生有用的次生代谢产物。在本研究中，从[具体宿主]中分离出两种该属的内生真菌。多基因系统发育研究表明，新描述的该属菌株是科学上新发现的，这是该宿主中该属的首次报道。其中一种发酵菌株[具体菌株名称](KUMCC 20 - 0268)产生了五种倍半萜类化合物，这些化合物先前已从沉香中报道过，其结构通过气相色谱 - 质谱联用(GC - MS)进行了鉴定。此外，还在体外研究了五种不同的培养基，以优化[具体真菌名称]和[另一种真菌名称]真菌生物量的生长条件。
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