School of Chemistry, University of Birmingham, Birmingham B15 2TT, U.K.
Biomacromolecules. 2020 Mar 9;21(3):1037-1059. doi: 10.1021/acs.biomac.9b01539. Epub 2020 Feb 26.
The advent of additive manufacturing offered the potential to revolutionize clinical medicine, particularly with patient-specific implants across a range of tissue types. However, to date, there are very few examples of polymers being used for additive processes in clinical settings. The state of the art with regards to 3D printable polymeric materials being exploited to produce novel clinically relevant implants is discussed here. We focus on the recent advances in the development of implantable, polymeric medical devices and tissue scaffolds without diverging extensively into bioprinting. By introducing the major 3D printing techniques along with current advancements in biomaterials, we hope to provide insight into how these fields may continue to advance while simultaneously reviewing the ongoing work in the field.
增材制造的出现为临床医学带来了革命性的变化，特别是在各种组织类型的患者特异性植入物方面。然而，迄今为止，在临床环境中使用聚合物进行增材制造的例子非常少。本文讨论了用于生产新型临床相关植入物的可 3D 打印聚合物材料的最新进展。我们专注于可植入聚合物医疗器械和组织支架的最新进展，而没有广泛涉及生物打印。通过介绍主要的 3D 打印技术以及生物材料的最新进展，我们希望能够深入了解这些领域如何在不断发展的同时，回顾该领域的现有工作。
