Conservative Dentistry Department, Cairo University, Egypt.
Oral Radiology Department, Egyptian Russian University, Egypt.
Clin Exp Dent Res. 2021 Oct;7(5):852-860. doi: 10.1002/cre2.429. Epub 2021 May 1.
This pilot survey aims to study the oral manifestations associated with COVID-19 infection and report the prevalence of oral signs and symptoms in COVID-19 patients.
From May 15 to June 10, 2020, we used an online questionnaire containing the oral manifestations that are expected to be associated with the COVID-19 infection. Adults in our survey who have been diagnosed with COVID-19 positive were confirmed with reverse transcriptase PCR (RT-PCR), and isolated in various hospitals in Cairo, Egypt.
This pilot study included 58 (53.4% males and 46.6% females) COVID-19 patients ages 18-46 years, and 13 (22.4%) were healthcare workers. Our results showed that 67.2% of the patients had at least one manifestation related to the oral cavity and salivary glands, and 32.8% (n = 19) did not have any symptoms associated with the oral cavity. The highest prevalence symptoms were dry mouth 39.7% (n = 23), gustatory dysfunction as 34.5% (n = 20) loss of salt sensation, 29.3% (n = 17) loss of sweet sensation, and 25.9% (n = 15) altered food taste, while the least prevalent symptoms were tongue redness 8.8% (n = 5), and gingival bleeding 7% (n = 4). The most frequently associated symptoms were loss of salt and sweetness, as reported by 27.6% of the participants. However, there was no significant association between the incidence of oral symptoms and demographic data (age, gender, or job) of the patients (p > 0.05).
Based on limited data, COVID-19 significantly impacts the oral cavity and salivary glands, as salivary gland-related symptoms and taste disorders are highly prevalent in COVID-19 patients.
本初步调查旨在研究与 COVID-19 感染相关的口腔表现,并报告 COVID-19 患者的口腔体征和症状的流行情况。
2020 年 5 月 15 日至 6 月 10 日,我们使用了一份包含预期与 COVID-19 感染相关的口腔表现的在线问卷。我们的调查对象为在埃及开罗的各医院确诊为 COVID-19 阳性的成年人,这些患者均经逆转录酶聚合酶链反应(RT-PCR)确诊。
本初步研究纳入了 58 名(53.4%为男性,46.6%为女性)18-46 岁的 COVID-19 患者,其中 13 名(22.4%)为医护人员。我们的结果显示,67.2%的患者至少有一种与口腔和唾液腺相关的表现,而 32.8%(n=19)的患者没有任何与口腔相关的症状。最常见的症状是口干 39.7%(n=23)、味觉障碍 34.5%(n=20)味觉减退、29.3%(n=17)甜味减退和 25.9%(n=15)食物味道改变,而最不常见的症状是舌头发红 8.8%(n=5)和牙龈出血 7%(n=4)。27.6%的参与者报告最常伴随的症状是味觉减退和甜味减退。然而,患者口腔症状的发生率与年龄、性别或职业等人口统计学数据之间无显著相关性(p>0.05)。
基于有限的数据,COVID-19 对口腔和唾液腺有显著影响,因为 COVID-19 患者唾液腺相关症状和味觉障碍的发生率较高。