Institute for Health Innovation and Technology (iHealthtech), National University of Singapore, Singapore, 117599, Singapore.
Department of Biomedical Engineering, National University of Singapore, Singapore, 117583, Singapore.
Adv Healthc Mater. 2021 Sep;10(17):e2100116. doi: 10.1002/adhm.202100116. Epub 2021 May 6.
Cardiovascular diseases account for the highest mortality globally, but recent advances in wearable technologies may potentially change how these illnesses are diagnosed and managed. In particular, continuous monitoring of cardiovascular vital signs for early intervention is highly desired. To this end, flexible wearable sensors that can be comfortably worn over long durations are gaining significant attention. In this review, advanced flexible wearable sensors for monitoring cardiovascular vital signals are outlined and discussed. Specifically, the functional materials, configurations, mechanisms, and recent advances of these flexible sensors for heart rate, blood pressure, blood oxygen saturation, and blood glucose monitoring are highlighted. Different mechanisms in bioelectric, mechano-electric, optoelectric, and ultrasonic wearable sensors are presented to monitor cardiovascular vital signs from different body locations. Present challenges, possible strategies, and future directions of these wearable sensors are also discussed. With rapid development, these flexible wearable sensors will potentially be applicable for both medical diagnosis and daily healthcare use in tackling cardiovascular diseases.
心血管疾病是全球范围内死亡率最高的疾病，但可穿戴技术的最新进展可能会改变这些疾病的诊断和管理方式。特别是，人们非常希望能够对心血管生命体征进行连续监测，以便及早进行干预。为此，人们越来越关注能够长时间舒适佩戴的柔性可穿戴传感器。在本综述中，概述并讨论了用于监测心血管生命体征的先进的柔性可穿戴传感器。具体而言，重点介绍了用于监测心率、血压、血氧饱和度和血糖监测的这些柔性传感器的功能材料、结构、机制和最新进展。介绍了生物电、机电、光电和超声可穿戴传感器的不同机制，以从不同身体部位监测心血管生命体征。还讨论了这些可穿戴传感器目前面临的挑战、可能的策略和未来发展方向。随着快速发展，这些柔性可穿戴传感器将有可能适用于心血管疾病的医疗诊断和日常保健应用。
