Cochen De Cock Valérie, Dotov Dobromir, Damm Loic, Lacombe Sandy, Ihalainen Petra, Picot Marie Christine, Galtier Florence, Lebrun Cindy, Giordano Aurélie, Driss Valérie, Geny Christian, Garzo Ainara, Hernandez Erik, Van Dyck Edith, Leman Marc, Villing Rudi, Bardy Benoit G, Dalla Bella Simone
Department of Neurology, Beau Soleil Clinic, Montpellier, France.
EuroMov Digital Health in Motion, University of Montpellier, IMT Mines Alès, Montpellier, France.
Front Psychol. 2021 Apr 26;12:655121. doi: 10.3389/fpsyg.2021.655121. eCollection 2021.
Taking regular walks when living with Parkinson's disease (PD) has beneficial effects on movement and quality of life. Yet, patients usually show reduced physical activity compared to healthy older adults. Using auditory stimulation such as music can facilitate walking but patients vary significantly in their response. An individualized approach adapting musical tempo to patients' gait cadence, and capitalizing on these individual differences, is likely to provide a rewarding experience, increasing motivation for walk-in PD. We aim to evaluate the observance, safety, tolerance, usability, and enjoyment of a new smartphone application. It was coupled with wearable sensors (BeatWalk) and delivered individualized musical stimulation for gait auto-rehabilitation at home. Forty-five patients with PD underwent a 1-month, outdoor, uncontrolled gait rehabilitation program, using the BeatWalk application (30 min/day, 5 days/week). The music tempo was being aligned in real-time to patients' gait cadence in a way that could foster an increase up to +10% of their spontaneous cadence. Open-label evaluation was based on BeatWalk use measures, questionnaires, and a six-minute walk test. Patients used the application 78.8% (±28.2) of the prescribed duration and enjoyed it throughout the program. The application was considered "easy to use" by 75% of the patients. Pain, fatigue, and falls did not increase. Fear of falling decreased and quality of life improved. After the program, patients improved their gait parameters in the six-minute walk test without musical stimulation. BeatWalk is an easy to use, safe, and enjoyable musical application for individualized gait rehabilitation in PD. It increases "walk for exercise" duration thanks to high observance. : ClinicalTrials.gov Identifier: NCT02647242.
帕金森病（PD）患者经常散步对运动和生活质量有益。然而，与健康的老年人相比，患者通常身体活动减少。使用音乐等听觉刺激可以促进步行，但患者的反应差异很大。一种根据患者步态节奏调整音乐节奏并利用这些个体差异的个性化方法，可能会带来有益的体验，增加PD患者步行的动力。我们旨在评估一款新的智能手机应用程序的依从性、安全性、耐受性、可用性和趣味性。它与可穿戴传感器（BeatWalk）相结合，在家中提供个性化的音乐刺激以进行步态自我康复。45名PD患者使用BeatWalk应用程序进行了为期1个月的户外非对照步态康复计划（每天30分钟，每周5天）。音乐节奏实时与患者的步态节奏对齐，以促进其自发节奏增加高达10%。开放标签评估基于BeatWalk使用措施、问卷和六分钟步行测试。患者使用该应用程序的时间占规定时长的78.8%（±28.2），并且在整个计划中都很喜欢它。75%的患者认为该应用程序“易于使用”。疼痛、疲劳和跌倒没有增加。跌倒恐惧减少，生活质量提高。在该计划之后，患者在没有音乐刺激的六分钟步行测试中改善了步态参数。BeatWalk是一款易于使用、安全且有趣的音乐应用程序，用于PD患者的个性化步态康复。由于高依从性，它增加了“为锻炼而步行”的时长。：ClinicalTrials.gov标识符：NCT02647242
