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在法国 COVID-19 第一波期间,养老院居民超额死亡的数量、随时间的变化、人口统计学特征和地理分布:一项全国性队列研究。

Magnitude, change over time, demographic characteristics and geographic distribution of excess deaths among nursing home residents during the first wave of COVID-19 in France: a nationwide cohort study.

机构信息

Univ Paris Est Creteil, Inserm, IMRB U955, CEpiA Team, F-94000 Creteil, France.

Public Health Department, APHP, Henri-Mondor Hospital, F-94000 Creteil, France.

出版信息

Age Ageing. 2021 Sep 11;50(5):1473-1481. doi: 10.1093/ageing/afab098.

DOI:10.1093/ageing/afab098
PMID:33984133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8406878/
Abstract

BACKGROUND

The objectives were to assess the excess deaths among Nursing Home (NH) residents during the first wave of the COVID-19 pandemic, to determine their part in the total excess deaths and whether there was a mortality displacement.

METHODS

We studied a cohort of 494,753 adults in 6,515 NHs in France exposed to COVID-19 pandemic (from 1 March to 31 May 2020) and compared with the 2014-2019 cohorts using data from the French National Health Data System. The main outcome was death. Excess deaths and standardized mortality ratios (SMRs) were estimated.

RESULT

There were 13,505 excess deaths. Mortality increased by 43% (SMR: 1.43). The mortality excess was higher among males than females (SMR: 1.51 and 1.38) and decreased with increasing age (SMRs in females: 1.61 in the 60-74 age group, 1.58 for 75-84, 1.41 for 85-94 and 1.31 for 95 or over; males: SMRs: 1.59 for 60-74, 1.69 for 75-84, 1.47 for 85-94 and 1.41 for 95 or over). No mortality displacement effect was observed up until 30 August 2020. By extrapolating to all NH residents nationally (N = 570,003), we estimated that they accounted for 51% of the general population excess deaths (N = 15,114 out of 29,563).

CONCLUSION

NH residents accounted for half of the total excess deaths in France during the first wave of the COVID-19 pandemic. The excess death rate was higher among males than females and among younger than older residents.

摘要

背景

本研究旨在评估新冠疫情第一波期间养老院(NH)居民的超额死亡人数,确定其在总超额死亡人数中的占比,以及是否存在死亡转移。

方法

我们研究了法国 6515 家 NH 中 494753 名成年人队列,这些人群在 2020 年 3 月 1 日至 5 月 31 日期间暴露于新冠疫情下,并使用法国国家卫生数据系统的数据与 2014-2019 年队列进行比较。主要结局为死亡。估计了超额死亡人数和标准化死亡率比(SMR)。

结果

共有 13505 例超额死亡。死亡率增加了 43%(SMR:1.43)。男性的死亡率高于女性(SMR:1.51 和 1.38),且随年龄增加而降低(女性的 SMRs:60-74 岁年龄组为 1.61,75-84 岁为 1.58,85-94 岁为 1.41,95 岁及以上为 1.31;男性:60-74 岁为 SMR 1.59,75-84 岁为 1.69,85-94 岁为 1.47,95 岁及以上为 1.41)。截至 2020 年 8 月 30 日,未观察到死亡转移效应。通过外推至全国所有 NH 居民(N=570033),我们估计他们占总人群超额死亡人数的 51%(29563 人中的 15114 人)。

结论

在新冠疫情第一波期间,NH 居民占法国总超额死亡人数的一半。男性的超额死亡率高于女性,年轻居民的超额死亡率高于老年居民。

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