Espiritu Jonathan, Meier Martin, Seitz Jan-Marten
Syntellix AG, Hannover, Germany.
Hannover Medical School, Hannover, Germany.
Bioact Mater. 2021 Apr 30;6(12):4360-4367. doi: 10.1016/j.bioactmat.2021.04.012. eCollection 2021 Dec.
Magnesium-based implants are re-emerging as a substantial amendment to standard orthopaedic implants. A brief introduction of magnesium (Mg) as a biodegradable material and basic magnetic resonance imaging (MRI) principles are discussed. This review aims to highlight the current performance of these implants during examinations with MRI. We also aim to summarise comparisons between Mg-based implants with current standards to emphasise the promotion of biodegradable implants in clinical practice. A comprehensive search of current literature on Mg-based implants and the utilisation of MRI in the studies was performed. Additionally, recorded artefact behaviour of Mg-based implants during MRI was investigated. A total of nine studies were included in which MRI was employed to image Mg-based implants. Of those studies, four of the nine discuss artefact production caused by the implants. MRI successfully imaged regions of interest over all and produced fewer artefacts than other materials used in the studies. MRI was employed in contrast angiography, bone growth observation, bone infection healing, and blood perfusion. Imaging capabilities of an implant material are vital to translating products into clinical application. Positive findings presented in this review suggest and support the use of Mg-based implants due to their successful visual compatibility with MRI techniques.
镁基植入物正作为标准骨科植入物的一项重大改进而重新兴起。本文讨论了作为可生物降解材料的镁(Mg)的简要介绍以及基本的磁共振成像(MRI)原理。本综述旨在突出这些植入物在MRI检查期间的当前性能。我们还旨在总结镁基植入物与当前标准之间的比较,以强调可生物降解植入物在临床实践中的推广。对当前关于镁基植入物的文献以及研究中MRI的应用进行了全面检索。此外,还研究了镁基植入物在MRI期间记录的伪影行为。总共纳入了九项使用MRI对镁基植入物进行成像的研究。在这些研究中,九项中有四项讨论了由植入物引起的伪影产生。MRI成功地对所有感兴趣区域进行了成像,并且产生的伪影比研究中使用的其他材料更少。MRI被用于对比血管造影、骨生长观察、骨感染愈合和血液灌注。植入材料的成像能力对于将产品转化为临床应用至关重要。本综述中呈现的积极结果表明并支持使用镁基植入物,因为它们与MRI技术具有成功的视觉兼容性。