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维生素 D 在新冠时代:来自 G.I.O.S.E.G. 专家小组的回顾与建议。

Vitamin D in the Covid-19 era: a review with recommendations from a G.I.O.S.E.G. expert panel.

机构信息

Institute of Endocrine and Metabolic Sciences (IEMS), San Raffaele Vita-Salute University, IRCCS San Raffaele Hospital, Via Olgettina 20, Milan, Italy.

IRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi, 4, Milan, Italy.

出版信息

Endocrine. 2021 Jun;72(3):597-603. doi: 10.1007/s12020-021-02749-3. Epub 2021 May 17.

DOI:10.1007/s12020-021-02749-3
PMID:33999367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8127472/
Abstract

Vitamin D (VITD) is a key hormone for bone health and has relevant extra-skeletal effects that might play a role in the prevention and treatment of COronaVIrus Disease 19 (COVID-19). Literature regarding this scenario is voluminous but controversial. Glucocorticoid Induced Osteoporosis Skeletal Endocrinology Group (G.I.O.S.E.G) has been present in the scientific debate about the use of VITD and has regularly interfaced national regulatory agencies to ensure appropriateness of its employment. Given the current pandemic and the questions on COVID-19 and VITD, G.I.O.S.E.G. appointed an expert panel to advise how to consider this issue best. The results of these deliberations are reported in the current recommendation paper.

摘要

维生素 D(VITD)是骨骼健康的关键激素,具有相关的骨骼外效应,可能在预防和治疗 COronaVIrus 病 19(COVID-19)方面发挥作用。关于这种情况的文献很多,但存在争议。糖皮质激素诱导的骨质疏松骨骼内分泌学组(G.I.O.S.E.G)一直参与关于 VITD 使用的科学辩论,并定期与国家监管机构进行沟通,以确保其使用的适当性。鉴于当前的大流行以及关于 COVID-19 和 VITD 的问题,G.I.O.S.E.G. 任命了一个专家小组,就如何最好地考虑这个问题提供建议。这些审议的结果在当前的推荐文件中报告。

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本文引用的文献

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Changes in 25-(OH) Vitamin D Levels during the SARS-CoV-2 Outbreak: Lockdown-Related Effects and First-to-Second Wave Difference-An Observational Study from Northern Italy.新型冠状病毒肺炎疫情期间25-(羟)维生素D水平的变化:封锁相关影响及第一波与第二波差异——来自意大利北部的一项观察性研究
Biology (Basel). 2021 Mar 19;10(3):237. doi: 10.3390/biology10030237.
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Patients hospitalized with COVID-19 have low levels of 25-hydroxyvitamin D.因新冠肺炎住院的患者25-羟维生素D水平较低。
Endocrine. 2021 Feb;71(2):267-269. doi: 10.1007/s12020-020-02597-7. Epub 2021 Jan 16.
4
Effects of Vitamin D on COVID-19 Infection and Prognosis: A Systematic Review.维生素D对新型冠状病毒肺炎感染及预后的影响:一项系统评价
Risk Manag Healthc Policy. 2021 Jan 7;14:31-38. doi: 10.2147/RMHP.S291584. eCollection 2021.
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Correction to: Endocrine and metabolic aspects of the COVID-19 pandemic.对《2019冠状病毒病大流行的内分泌和代谢方面》的更正
Rev Endocr Metab Disord. 2021 Mar;22(1):145. doi: 10.1007/s11154-020-09620-2.
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