Anhui Provincial Tuberculosis Institute, Hefei, Anhui, China.
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
J Evid Based Med. 2021 May;14(2):123-138. doi: 10.1111/jebm.12430. Epub 2021 May 18.
Exposure to air pollutants has been associated with respiratory viral infections. Epidemiological studies have shown that air pollution exposure is related to increased cases of SARS-COV-2 infection and COVID-19-associated mortality. In addition, the changes of meteorological parameters have also been implicated in the occurrence and development of COVID-19. However, the molecular mechanisms by which pollutant exposure and changes of meteorological parameters affects COVID-19 remains unknown. This review summarizes the biology of COVID-19 and the route of viral transmission, and elaborates on the relationship between air pollution and climate indicators and COVID-19. Finally, we envisaged the potential roles of air pollution and meteorological parameters in COVID-19.
暴露于空气污染物与呼吸道病毒感染有关。流行病学研究表明,空气污染暴露与 SARS-CoV-2 感染病例增加和 COVID-19 相关死亡率升高有关。此外,气象参数的变化也与 COVID-19 的发生和发展有关。然而,污染物暴露和气象参数变化影响 COVID-19 的分子机制尚不清楚。本综述总结了 COVID-19 的生物学和病毒传播途径,并详细阐述了空气污染与气候指标和 COVID-19 之间的关系。最后,我们设想了空气污染和气象参数在 COVID-19 中的潜在作用。