Department of Neurosurgery, University of Michigan, Ann Arbor, MI, 48105, USA.
Department of Neurosurgery, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, R5018 BSRB, MI, 48109-2200, USA.
Fluids Barriers CNS. 2021 May 21;18(1):24. doi: 10.1186/s12987-021-00258-z.
This editorial discusses advances in brain barrier and brain fluid research in 2020. Topics include: the cerebral endothelium and the neurovascular unit; the choroid plexus; the meninges; cerebrospinal fluid and the glymphatic system; disease states impacting the brain barriers and brain fluids; drug delivery to the brain. This editorial also highlights the recently completed Fluids Barriers CNS thematic series entitled, 'Advances in in vitro modeling of the blood-brain barrier and neurovascular unit'. Such in vitro modeling is progressing rapidly.
本社论讨论了 2020 年在脑屏障和脑液研究方面的进展。主题包括:大脑内皮细胞和神经血管单元;脉络丛;脑膜;脑脊液和脑淋巴系统;影响脑屏障和脑液的疾病状态;药物递送到大脑。本社论还重点介绍了最近完成的题为“血脑屏障和神经血管单元体外模型研究进展”的《中枢神经系统液流屏障专题系列》。这种体外模型正在迅速发展。