Su Qi, Liu Qin
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.
Front Nutr. 2021 May 10;8:644138. doi: 10.3389/fnut.2021.644138. eCollection 2021.
There is a growing recognition that a good diet can help people maintain mental and physical health, while a bad one will cause the disorder of body function, and even lead to several diseases. A lot of attentions have been devoted to analyze every possible health-related factor in the daily diet, including food ingredients, additives, and cooking process. With the support of high-throughput sequencing technology, there is accumulating evidence gradually clarifying that most of these factors are mainly through the interactions with gut microbiome to trigger downstream effects. The gut microbiome may be able to act as a very sensitive mirror in response to human daily diet. A complex network of interactions among diet, gut microbiome, and health has been gradually depicted, but it is rarely discussed from a more comprehensive perspective. To this end, this review summarized the latest updates in diet-gut microbiome interactions, analyzed most identified factors involved in this process, showed the possibility of maintaining health or alleviating diseases by diet intervention, aiming to help people choose a suitable recipe more accurately.
人们越来越认识到，良好的饮食有助于人们保持身心健康，而不良的饮食则会导致身体功能紊乱，甚至引发多种疾病。人们已投入大量精力来分析日常饮食中每一个可能与健康相关的因素，包括食物成分、添加剂和烹饪过程。在高通量测序技术的支持下，越来越多的证据逐渐表明，这些因素大多主要通过与肠道微生物群的相互作用来引发下游效应。肠道微生物群可能能够作为反映人类日常饮食的非常敏感的镜子。饮食、肠道微生物群和健康之间复杂的相互作用网络已逐渐被描绘出来，但很少从更全面的角度进行讨论。为此，本综述总结了饮食与肠道微生物群相互作用的最新进展，分析了该过程中最确定的因素，展示了通过饮食干预维持健康或缓解疾病的可能性，旨在帮助人们更准确地选择合适的食谱。
