Angeles-Agdeppa Imelda, Nacis Jacus S, Capanzana Mario V, Dayrit Fabian M, Tanda Keith V
Department of Science and Technology, Food and Nutrition Research Institute, Taguig City 1631, Philippines.
Department of Chemistry, Ateneo de Manila University, Quezon City 1108, Philippines.
J Funct Foods. 2021 Aug;83:104557. doi: 10.1016/j.jff.2021.104557. Epub 2021 May 24.
Understanding the complex pathogenesis of COVID-19 continues to evolve. With observation and quarantine as the prevailing standard of care, this study evaluated the effects of virgin coconut oil (VCO) in the biochemical markers of suspect and probable cases of COVID-19. A 28-day randomized, double-blind, controlled intervention was conducted among 63 adults in two isolation facilities in Santa Rosa City, Laguna, Philippines. The participants were randomly assigned to receive either a standardized meal (control) or a standardized meal mixed with a predefined dosage of VCO. Changes in clinical markers were measured at three time points (day 0, 14, and 28), with daily monitoring of COVID-19 symptoms. Participants in the intervention group showed a significant decline in the C-reactive protein level, with the mean CRP level normalized to ≤ 5 mg/dL on the 14th day of the intervention. As an adjunct therapy, meals mixed with VCO is effective fostering faster recovery from COVID-19.
对新冠病毒复杂发病机制的理解仍在不断发展。鉴于观察和隔离是主要的护理标准,本研究评估了初榨椰子油(VCO)对新冠病毒疑似和确诊病例生化指标的影响。在菲律宾拉古纳省圣罗莎市的两个隔离设施中,对63名成年人进行了为期28天的随机、双盲、对照干预。参与者被随机分配接受标准化膳食(对照组)或与预定义剂量VCO混合的标准化膳食。在三个时间点(第0天、第14天和第28天)测量临床指标的变化,并每日监测新冠病毒症状。干预组参与者的C反应蛋白水平显著下降,在干预第14天时,平均CRP水平恢复正常至≤5mg/dL。作为辅助治疗,与VCO混合的膳食可有效促进新冠病毒感染后的更快康复。