Keap1/Nrf2信号通路。
Keap1/Nrf2 Signaling Pathway.
作者信息
Sykiotis Gerasimos P
机构信息
Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital, 1011 Lausanne, Switzerland.
Faculty of Biology and Medicine, University of Lausanne, 1011 Lausanne, Switzerland.
出版信息
Antioxidants (Basel). 2021 May 22;10(6):828. doi: 10.3390/antiox10060828.
Abstract
Nuclear factor, erythroid 2-like transcription factor 2 (Nrf2) and its cytoplasmic inhibitor, kelch-like ECH-associated protein 1 (Keap1), comprise a redox-responsive endogenous antioxidant defense module that orchestrates the expression of cytoprotective genes to maintain homeostasis [...].
摘要
核因子红系2样转录因子2（Nrf2）及其胞质抑制剂kelch样ECH相关蛋白1（Keap1）构成一个氧化还原反应性内源性抗氧化防御模块，该模块协调细胞保护基因的表达以维持体内平衡[...]。
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