Tabone Trevor, Koulaouzidis Anastasios, Ellul Pierre
Gastroenterology Department, Mater Dei Hospital, MSD 2090 Msida, Malta.
Department of Social Medicine & Public Health, Pomeranian Medical University, 70-204 Szczecin, Poland.
J Clin Med. 2021 May 28;10(11):2372. doi: 10.3390/jcm10112372.
In the constantly developing era of minimal diagnostic invasiveness, the role of colon capsule endoscopy in colonic examination is being increasingly recognised, especially in the context of curtailed endoscopy services due to the COVID-19 pandemic. It is a safe diagnostic tool with low adverse event rates. As with other endoscopic modalities, various colon capsule endoscopy scores allow the standardisation of reporting and reproducibility. As bowel cleanliness affects CCE's diagnostic yield, a few operator-dependent scores (Leighton-Rex and CC-CLEAR scores) and a computer-dependent score (CAC score) have been developed to grade bowel cleanliness objectively. CCE can be used to monitor IBD mucosal disease activity through the UCEIS and the panenteric CECDAIic score for UC and CD, respectively. CCE may also have a role in CRC screening, given similar sensitivity and specificity rates to conventional colonoscopy to detect colonic polyps ≥ 10 mm and CRC. Given CCE's diagnostic yield and reproducible clinical scores with high inter-observer agreements, CCE is fast becoming a suitable alternative to conventional colonoscopy in specific patient populations.
在诊断侵入性不断降低的时代，结肠胶囊内镜在结肠检查中的作用日益得到认可，尤其是在因新冠疫情导致内镜检查服务受限的情况下。它是一种安全的诊断工具，不良事件发生率低。与其他内镜检查方式一样，各种结肠胶囊内镜评分有助于实现报告标准化和可重复性。由于肠道清洁度会影响结肠胶囊内镜的诊断率，因此已经开发了一些依赖操作者的评分（Leighton-Rex评分和CC-CLEAR评分）和一种依赖计算机的评分（CAC评分）来客观评估肠道清洁度。结肠胶囊内镜可分别通过UCEIS以及针对溃疡性结肠炎（UC）和克罗恩病（CD）的全肠道CECDAIic评分来监测炎症性肠病（IBD）的黏膜疾病活动情况。鉴于结肠胶囊内镜在检测≥10毫米的结肠息肉和结直肠癌方面的敏感性和特异性与传统结肠镜检查相似，它在结直肠癌筛查中也可能发挥作用。鉴于结肠胶囊内镜的诊断率以及具有较高观察者间一致性的可重复临床评分，它正迅速成为特定患者群体中传统结肠镜检查的合适替代方法。
