Jenkins D J, Wolever T M, Buckley G, Lam K Y, Giudici S, Kalmusky J, Jenkins A L, Patten R L, Bird J, Wong G S
Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Canada.
Am J Clin Nutr. 1988 Aug;48(2):248-54. doi: 10.1093/ajcn/48.2.248.
Eight patients with noninsulin-dependent diabetes underwent two 2-wk study periods in random order during which they were provided with carbohydrate foods with either a high or low glycemic index (GI). Over both high-GI and low-GI periods there were significant reductions in body weight, serum fructosamine, and cholesterol. Reductions in fasting blood glucose, HbA1c, and urinary c-peptide-to-creatinine ratio were significant only over the low-GI period despite a smaller mean weight loss. Reductions in triglyceride were significant only over the high-GI diet. Inclusion of low-GI foods into diets of patients with diabetes may be an additional measure that favorably influences carbohydrate metabolism without increasing insulin demand.
八名非胰岛素依赖型糖尿病患者按随机顺序接受了两个为期2周的研究阶段，在此期间，他们被给予高血糖指数（GI）或低血糖指数的碳水化合物食物。在高GI期和低GI期，体重、血清果糖胺和胆固醇均有显著降低。尽管平均体重减轻较少，但空腹血糖、糖化血红蛋白（HbA1c）和尿C肽与肌酐比值仅在低GI期有显著降低。甘油三酯仅在高GI饮食期间有显著降低。将低GI食物纳入糖尿病患者的饮食中可能是一种额外的措施，可在不增加胰岛素需求的情况下对碳水化合物代谢产生有利影响。
