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非药物干预措施对 37 个经合组织成员国 COVID-19 疫情增长的影响。

The impact of non-pharmaceutical interventions on COVID-19 epidemic growth in the 37 OECD member states.

机构信息

Evidence-Based Public Health Unit, Centre for International Health Protection, Robert Koch Institute, Nordufer 20, 13353, Berlin, Germany.

Centre for International Health Protection, Robert Koch Institute, Nordufer 20, 13353, Berlin, Germany.

出版信息

Eur J Epidemiol. 2021 Jun;36(6):629-640. doi: 10.1007/s10654-021-00766-0. Epub 2021 Jun 10.

Abstract

We estimated the impact of a comprehensive set of non-pharmeceutical interventions on the COVID-19 epidemic growth rate across the 37 member states of the Organisation for Economic Co-operation and Development during the early phase of the COVID-19 pandemic and between October and December 2020. For this task, we conducted a data-driven, longitudinal analysis using a multilevel modelling approach with both maximum likelihood and Bayesian estimation. We found that during the early phase of the epidemic: implementing restrictions on gatherings of more than 100 people, between 11 and 100 people, and 10 people or less was associated with a respective average reduction of 2.58%, 2.78% and 2.81% in the daily growth rate in weekly confirmed cases; requiring closing for some sectors or for all but essential workplaces with an average reduction of 1.51% and 1.78%; requiring closing of some school levels or all school levels with an average reduction of 1.12% or 1.65%; recommending mask wearing with an average reduction of 0.45%, requiring mask wearing country-wide in specific public spaces or in specific geographical areas within the country with an average reduction of 0.44%, requiring mask-wearing country-wide in all public places or all public places where social distancing is not possible with an average reduction of 0.96%; and number of tests per thousand population with an average reduction of 0.02% per unit increase. Between October and December 2020 work closing requirements and testing policy were significant predictors of the epidemic growth rate. These findings provide evidence to support policy decision-making regarding which NPIs to implement to control the spread of the COVID-19 pandemic.

摘要

我们评估了一套非药物干预措施对经济合作与发展组织 37 个成员国 COVID-19 疫情增长率的影响,研究时间段为 COVID-19 大流行早期以及 2020 年 10 月至 12 月。为完成这项任务,我们采用数据驱动的纵向分析方法,利用最大似然和贝叶斯估计,采用多层次建模方法。我们发现,在疫情早期:实施对 100 人以上、11-100 人和 10 人或以下聚集活动的限制,与每周确诊病例日增长率分别平均降低 2.58%、2.78%和 2.81%相关;要求关闭部分或全部但基本工作场所,平均减少 1.51%和 1.78%;要求关闭部分或全部学校级别,平均减少 1.12%或 1.65%;建议佩戴口罩,平均减少 0.45%;要求在全国特定公共场所或全国特定地理区域佩戴口罩,平均减少 0.44%;要求在全国所有公共场所或所有无法保持社交距离的公共场所佩戴口罩,平均减少 0.96%;每千人口检测次数增加,平均减少 0.02%。2020 年 10 月至 12 月,工作场所关闭要求和检测政策是疫情增长率的重要预测因素。这些发现为支持政策决策提供了证据,以确定应实施哪些非药物干预措施来控制 COVID-19 疫情的传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6988/8332634/037033d391f5/10654_2021_766_Fig1_HTML.jpg

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