Beal S M, Blundell H K
Adelaide Children's Hospital, North Adelaide, Australia.
Arch Dis Child. 1988 Aug;63(8):924-30. doi: 10.1136/adc.63.8.924.
The incidence of sudden infant death syndrome (SIDS) between birth and 2 years of age in South Australia was found to be 2.1/1000 live births. The incidence in previous siblings was 10 times that expected, in second degree relatives five times, and in third degree relatives four times that expected for the community. The minimum incidence in the next subsequent sibling was five times that expected. Except for one family in which both twins died during the same night, the surviving twin has never died (23 infants). The incidence of SIDS in adopted infants was similar to the incidence in natural born infants. Families in which two or more siblings died from SIDS differed from families in which only one infant died from SIDS in several ways. More infants were over 12 months old, and the mothers had an increased incidence of previous miscarriage and threatened miscarriage during the pregnancy with the infant who died. In one family both infants had bronchomalacia, and two families were severely socially deprived. For most families (92%) in which an infant died from SIDS the risk of recurrence is small (less that twice the expected risk). We have identified a small subgroup (8%) with a significantly increased risk of recurrence.
在南澳大利亚，出生至2岁婴儿的婴儿猝死综合征（SIDS）发病率为2.1/1000活产儿。前同胞的发病率是预期发病率的10倍，二级亲属是5倍，三级亲属是社区预期发病率的4倍。下一个同胞的最低发病率是预期发病率的5倍。除了一个家庭中双胞胎在同一晚死亡外，幸存的双胞胎从未死亡（23名婴儿）。领养婴儿的SIDS发病率与自然出生婴儿的发病率相似。有两个或更多同胞死于SIDS的家庭与只有一名婴儿死于SIDS的家庭在几个方面存在差异。更多婴儿超过12个月大，而且在死于SIDS的婴儿的孕期，母亲既往流产和先兆流产的发生率更高。在一个家庭中，两名婴儿都患有支气管软化症，还有两个家庭社会经济状况严重匮乏。对于大多数有婴儿死于SIDS的家庭（92%），复发风险很小（低于预期风险的两倍）。我们已经确定了一个复发风险显著增加的小亚组（8%）。
