Al'perina E L, Eliseeva L S
Fiziol Zh SSSR Im I M Sechenova. 1988 May;74(5):682-6.
The participation of the pituitary gland in the actualization of dopamine-dependent immune response after removal of adrenals and an increase in the serotonin content, was studied in the CBA mice. A lesion of the pituitary stalk prevented the activation of immune response usually observed in adrenalectomized animals treated with serotonin. The data obtained suggest that exclusion of the serotoninergic immunomodulating pathways out of the CNS causes the predominance of dopaminergic system. Activating action of the latter on the immunity is actualized via the hypophysis and subsequently maintained by central mechanisms.
在CBA小鼠中，研究了垂体在摘除肾上腺后实现多巴胺依赖性免疫反应以及血清素含量增加过程中的作用。垂体柄损伤阻止了通常在接受血清素治疗的肾上腺切除动物中观察到的免疫反应激活。所获得的数据表明，中枢神经系统中血清素能免疫调节途径的排除导致多巴胺能系统占主导地位。后者对免疫的激活作用通过垂体实现，随后由中枢机制维持。
