胃肠道微生物群对C3H/HeJ小鼠诱导和维持卵清蛋白口服耐受性的影响。
Effect of the gastrointestinal microflora on induction and maintenance of oral tolerance to ovalbumin in C3H/HeJ mice.
作者信息
Moreau M C, Corthier G
机构信息
Laboratoire d'Ecologie Microbienne, CRJJ, INRA, Jouy-en-Josas, France.
出版信息
Infect Immun. 1988 Oct;56(10):2766-8. doi: 10.1128/iai.56.10.2766-2768.1988.
Abstract
The effect of the digestive microflora on oral tolerance to ovalbumin was studied by using axenic (germfree) and conventional C3H/HeJ mice. In contrast to reported results of studies with sheep erythrocytes, oral administration of ovalbumin induced tolerance in axenic mice, but the maintenance of tolerance was found to be of shorter duration than was with conventional mice. These data indicate that the contribution of the microflora to oral tolerance depends on the antigen used.
摘要
通过使用无菌（无特定病原体）和常规的C3H/HeJ小鼠，研究了消化微生物群对卵清蛋白口服耐受性的影响。与用绵羊红细胞进行的研究报告结果相反，口服卵清蛋白可诱导无菌小鼠产生耐受性，但发现这种耐受性的维持时间比常规小鼠短。这些数据表明，微生物群对口服耐受性的贡献取决于所使用的抗原。
相似文献
1
Effect of the gastrointestinal microflora on induction and maintenance of oral tolerance to ovalbumin in C3H/HeJ mice.胃肠道微生物群对C3H/HeJ小鼠诱导和维持卵清蛋白口服耐受性的影响。
Infect Immun. 1988 Oct;56(10):2766-8. doi: 10.1128/iai.56.10.2766-2768.1988.
2
Colonization of gnotobiotic mice with human gut microflora at birth protects against Escherichia coli heat-labile enterotoxin-mediated abrogation of oral tolerance.
Pediatr Res. 2003 Nov;54(5):739-46. doi: 10.1203/01.PDR.0000086902.52137.C9. Epub 2003 Aug 6.
3
Oral tolerance to ovalbumin in mice: induction and long-term persistence unaffected by Staphylococcus aureus enterotoxin B and Clostridium perfringens type A enterotoxin.小鼠对卵清蛋白的口服耐受：诱导及长期持续性不受金黄色葡萄球菌肠毒素B和A型产气荚膜梭菌肠毒素的影响。
Pediatr Res. 1997 Oct;42(4):503-8. doi: 10.1203/00006450-199710000-00014.
4
The absence of gut flora, the doses of antigen ingested and aging affect the long-term peripheral tolerance induced by ovalbumin feeding in mice.肠道菌群的缺失、摄入抗原的剂量以及衰老都会影响通过给小鼠喂食卵清蛋白诱导的长期外周耐受。
Res Immunol. 1996 Jan;147(1):49-59. doi: 10.1016/0923-2494(96)81548-3.
5
6
Role of intestinal bacterial flora in oral tolerance induction.肠道菌群在口服耐受诱导中的作用。
Histol Histopathol. 2004 Jul;19(3):907-14. doi: 10.14670/HH-19.907.
7
Genetics of susceptibility to oral tolerance to ovalbumin.对卵清蛋白口服耐受易感性的遗传学
Braz J Med Biol Res. 1987;20(6):785-90.
8
The absence of gut flora has no effect on the induction of oral tolerance to ovalbumin.肠道菌群的缺失对诱导针对卵清蛋白的口服耐受性没有影响。
Adv Exp Med Biol. 1995;371B:1239-41.
9
Lack of oral tolerance in C3H/HeJ mice.C3H/HeJ小鼠中缺乏口服耐受。
J Exp Med. 1982 Feb 1;155(2):605-10. doi: 10.1084/jem.155.2.605.
10
Induction of ovalbumin-specific tolerance by oral administration of Lactococcus lactis secreting ovalbumin.通过口服分泌卵清蛋白的乳酸乳球菌诱导卵清蛋白特异性耐受。
Gastroenterology. 2007 Aug;133(2):517-28. doi: 10.1053/j.gastro.2007.04.073. Epub 2007 May 3.
引用本文的文献
1
Chronic Inflammation Offers Hints About Viable Therapeutic Targets for Preeclampsia and Potentially Related Offspring Sequelae.慢性炎症为子痫前期及潜在相关子代后遗症提供了可行治疗靶点的线索。
Int J Mol Sci. 2024 Dec 3;25(23):12999. doi: 10.3390/ijms252312999.
2
HHuMin-U Activates Innate Immune Defense against Norovirus Infection through TBK1-IRF3 and NF-κB Signaling Pathways.HHuMin-U通过TBK1-IRF3和NF-κB信号通路激活针对诺如病毒感染的固有免疫防御。
Research (Wash D C). 2022 Dec 19;2022:0007. doi: 10.34133/research.0007. eCollection 2022.
3
Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases.肠道微生物群与先天免疫的相互作用及其在自身免疫性疾病中的意义。
Front Immunol. 2020 Feb 21;11:282. doi: 10.3389/fimmu.2020.00282. eCollection 2020.
4
Cross-Domain and Viral Interactions in the Microbiome.微生物组中的跨域和病毒相互作用。
Microbiol Mol Biol Rev. 2019 Jan 9;83(1). doi: 10.1128/MMBR.00044-18. Print 2019 Mar.
5
Low-complexity microbiota in the duodenum of children with newly diagnosed ulcerative colitis.新诊断溃疡性结肠炎患儿十二指肠中低复杂性微生物群
PLoS One. 2017 Oct 19;12(10):e0186178. doi: 10.1371/journal.pone.0186178. eCollection 2017.
6
An expanding stage for commensal microbes in host immune regulation.共生微生物在宿主免疫调节中的扩展阶段。
Cell Mol Immunol. 2017 Apr;14(4):339-348. doi: 10.1038/cmi.2016.64. Epub 2017 Jan 9.
7
Staphylococcus aureus convert neonatal conventional CD4(+) T cells into FOXP3(+) CD25(+) CD127(low) T cells via the PD-1/PD-L1 axis.金黄色葡萄球菌通过 PD-1/PD-L1 轴将新生常规 CD4(+) T 细胞转化为 FOXP3(+) CD25(+) CD127(low) T 细胞。
Immunology. 2014 Mar;141(3):467-81. doi: 10.1111/imm.12209.
8
The microbiome and regulation of mucosal immunity.微生物组与黏膜免疫的调控。
Immunology. 2014 May;142(1):24-31. doi: 10.1111/imm.12231.
9
Neonatal mucosal immune stimulation by microbial superantigen improves the tolerogenic capacity of CD103(+) dendritic cells.新生儿黏膜免疫刺激物通过微生物超抗原改善 CD103(+)树突状细胞的耐受原性。
PLoS One. 2013 Sep 27;8(9):e75594. doi: 10.1371/journal.pone.0075594. eCollection 2013.
10
Role of the gut microbiota in immunity and inflammatory disease.肠道微生物群在免疫和炎症性疾病中的作用。
Nat Rev Immunol. 2013 May;13(5):321-35. doi: 10.1038/nri3430.
本文引用的文献
1
Lack of oral tolerance in C3H/HeJ mice.C3H/HeJ小鼠中缺乏口服耐受。
J Exp Med. 1982 Feb 1;155(2):605-10. doi: 10.1084/jem.155.2.605.
2
3
[Relationship between the development of the intestinal IgA immune system and the establishment of microbial flora in the digestive tract of young holoxenic mice].
Ann Immunol (Paris). 1982 Jul-Aug;133D(1):29-39.
4
Induction of oral tolerance in mice unresponsive to bacterial lipopolysaccharide.诱导对细菌脂多糖无反应的小鼠产生口服耐受。
Infect Immun. 1983 Sep;41(3):1383-5. doi: 10.1128/iai.41.3.1383-1385.1983.
5
Two distinct antigen-specific suppressor factors induced by the oral administration of antigen.经口服抗原诱导产生的两种不同的抗原特异性抑制因子。
J Exp Med. 1980 Sep 1;152(3):545-54. doi: 10.1084/jem.152.3.545.
6
Lipopolysaccharide (LPS) regulation of the immune response: LPS influence on oral tolerance induction.脂多糖（LPS）对免疫反应的调节：LPS对口服耐受诱导的影响。
J Immunol. 1982 May;128(5):1992-8.
7
Immunoregulation of IgE responses: the role of the gut in perspective.IgE反应的免疫调节：肠道作用的展望
Ann Allergy. 1984 Dec;53(6 Pt 2):550-6.
8
Development of immunological capacity under germfree and conventional conditions.无菌和常规条件下免疫能力的发展。
Ann N Y Acad Sci. 1983 Jun 30;409:96-113. doi: 10.1111/j.1749-6632.1983.tb26862.x.
9
10
The gut-associated lymphoid system: nature and properties of the large dividing cells.肠道相关淋巴系统：大型分裂细胞的性质与特征
Eur J Immunol. 1974 Jun;4(6):435-43. doi: 10.1002/eji.1830040610.
Zotero 插件